TETRAMETHYLURIC ACID Raw Materials powder

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TETRAMETHYLURIC ACID powder Usage and Synthesis.

Theophylline is a methyl purine drug. It has the effects of strengthening the heart, diuresis, dilating coronary arteries, relaxing bronchial smooth muscles and stimulating the central nervous system. It is mainly used to treat bronchial asthma, emphysema, bronchitis, cardiac dyspnea, etc.

Uses of TETRAMETHYLURIC ACID powder.

Medical application: Mainly used to treat respiratory diseases such as bronchial asthma and emphysema, thanks to its ability to dilate bronchi and relax smooth muscles.

Industrial application: As an intermediate for pesticides and dyes, tetramethyluric acid is also widely used in chemical production and can be used for raw material synthesis.

Function of TETRAMETHYLURIC ACID.

Tetramethyluric acid, also known as theophylline, belongs to the methyl purine class of drugs. It has multiple pharmacological effects such as cardiotonic, diuretic, coronary artery dilation, bronchial smooth muscle relaxation and central nervous system excitation.

Synthesis process of Bulk TETRAMETHYLURIC ACID.

1,3-Dimethylbarbituric acid was synthesized with DMM and 1,3-dimethylurea as raw materials and sodium methoxide as catalyst, and the reaction yield was 76.21%. 6-Chloro-1,3-dimethylpyrimidine-2,4-dione was synthesized with 1,3-dimethylbarbituric acid and phosphorus oxychloride as raw materials, and the reaction yield was 85.28%. Then, 6-chloro-1,3-dimethylpyrimidine-2,4-dione was reacted with methylamine to synthesize 1,3-dimethyl-6-methylaminopyrimidine-2,4-dione. -methylaminopyrimidine-2,4-dione was used as the raw material, and 1,3-dimethyl-5,6-dimethylaminopyrimidine-2,4-dione was synthesized through a two-step reaction; 1,3-dimethyl-5,6-dimethylaminopyrimidine-2,4-dione and triphosgene were used as raw materials to synthesize the target product 1,3,7,9-tetramethyluric acid. The reaction temperature and raw material ratio were optimized, and the optimal reaction conditions were obtained: the reaction temperature was 30℃, and the raw material ratio was 1,3-dimethyl-5,6-dimethylaminopyrimidine-2,4-dione: triphosgene = 1:1.2

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