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L-Asparagine has a melting point of 234-235° and can form a special aroma substance by aminocarbonyl reaction with sugar cohesion. The best crystallization method is water, followed by Ethanol. It is hydrolyzed to aspartic acid by alkali. Its aqueous solution also decomposes when heated. Soluble in water (3g/100L, 25℃), almost insoluble in ethanol and ether. The aqueous solution is acidic. Not Essential amino acid. If deficient, it affects development and regulates the metabolic function of brain and nerve cells. Naturally found in various legumes, etc.
Pharmacokinetics of L-Asparagine:
L-Asparagine is generally isolated from aqueous extracts of bean sprouts from lupins and soybeans with high L-asparagine content. It can also be obtained by acylation of L-aspartic acid with ammonium hydroxide. It is also obtained by amination of L-aspartic acid with ammonium hydroxide. Intravenous administration induces a decrease in blood pressure, peripheral vasodilation, increased cardiac contractility, slower heart rate and increased urine output. When administered orally to pylorus-ligated rats, it prevented the gastric effects caused by oral administration of Acetylsalicylic acid can prevent gastric mucosal damage caused by oral administration. Animal tests have shown that it has a significant cough suppressant effect and a certain effect on asthma.
Clinical Application of L-Asparagine:
L-Asparagine is used as a drug for hypotension, bronchodilatation (asthma), anti-peptic ulcer and gastric dysfunction. It is used in microbial culture, propylene It is used in microbial culture, sewage treatment of acrylonitrile, etc. It can also be used as a nutritional supplement and has a wide range of applications in medicine, food and daily chemicals. In medicine, it can be used for In medicine, it can be used to treat heart disease, liver disease, hypertension, and has the effect of preventing and restoring fatigue. In the food industry, it is a good nutritional supplement and is added to various refreshing drinks. It is also a sweetener. In the chemical industry, it can be used as a raw material for the manufacture of synthetic resins. It can also be used as a nutritional additive in cosmetics, etc.
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