Topiramate powder Raw Materials CAS 97240-79-4
Topiramate powder Raw Materials CAS 97240-79-4
Topiramate powder Raw Materials CAS 97240-79-4
Topiramate powder Raw Materials CAS 97240-79-4
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Topiramate powder Raw Materials CAS 97240-79-4

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Product details

Uses and synthesis of Topiramate powder

Anti-epileptic: For the treatment of partial-onset seizures, generalized tonic-clonic seizures, and Lennox-Gastaut syndrome in adults and children. Can be used as a single drug or in combination with other anti-epileptic drugs.

Migraine prevention: For the preventive treatment of migraine in adults

Topiramate powder

Topiramate powder's mechanism of action

Blocks voltage-dependent sodium channels: Reduces overexcitation of neurons.

Enhances the activity of gamma-aminobutyric acid (GABA): GABA is an inhibitory neurotransmitter that inhibits neuronal excitability.

Antagonizes glutamate receptors (AMPA/kainate subtypes): Glutamate is an excitatory neurotransmitter and topiramate can weaken its effects.

Inhibits carbonic anhydrase: This effect may be related to its role in preventing migraines.

Topiramate

Target Group of Topiramate powder

Pregnant and breastfeeding women: Not allowed.

Children: Can be used to treat certain types of epilepsy, but the dose needs to be adjusted according to weight.

Elderly: The dose may need to be adjusted.


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