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Uses of Obeticholic Acid powderBile acid synthesis and transport: OCA inhibits the synthesis of bile acids in the liver and promotes the excretion of bile acids from the liver into the bile duct, thereby reducing the accumulation of bile acids in the liver.
Hepatic inflammation and fibrosis: OCA can reduce liver inflammation and fibrosis, two pathological processes that are key features of many chronic liver diseases.
Glucose and lipid metabolism: FXR also plays a role in glucose and lipid metabolism, and the activation of OCA may have an impact on these metabolic processes.
Applications of Obeticholic Acid powder
Primary Biliary Cholangitis (PBC): PBC is a chronic autoimmune liver disease characterized by progressive destruction of the small bile ducts within the liver. OCA may be used in patients with PBC who have an inadequate response to or are unable to tolerate ursodeoxycholic acid (UDCA).Nonalcoholic Steatohepatitis (NASH): NASH is a liver disease associated with abnormal accumulation of fat in the liver, which can lead to liver inflammation and fibrosis. OCA is being studied for the treatment of NASH-related liver fibrosis.
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