Diclofenac sodium powder Raw Materials CAS 15307-79-6

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Uses and synthesis of Diclofenac sodium powder

Diclofenac sodium powder is a white crystalline powder known as Voltaline, Diclofenac sodium powder, and pantalin. It is a non-steroidal anti-inflammatory drug (NSAID) derived from phenylacetic acid. Diclofenac sodium is mainly used in the treatment of osteoarthritis, rheumatoid arthritis, polymyositis, dermatomyositis, spondyloarthropathy, ankylosing spondylitis and other acute pain relief. Diclofenac sodium powder is a fast-acting nonsteroidal anti-inflammatory drug that produces analgesic, anti-inflammatory and antipyretic effects by inhibiting the synthesis of prostaglandins.

Applications/Functions of Diclofenac sodium powder

• Diclofenac sodium powder is a powerful antipyretic, analgesic and anti-inflammatory drug. Its anti-inflammatory effect is 2-2.5 times that of indomethacin and 26-50 times stronger than acetylsalicylic acid. It is suitable for rheumatoid arthritis, osteoarthropathy, pain relief after operation and fever caused by various reasons.
• Standard NSAID and cyclooxygenase (COX) inhibitors; Diclofenac sodium is used as a selective substrate for CYP2C9.

Physicochemical Property of Diclofenac sodium powder

Diclofenac sodium colorless crystalline powder. Melting point 283-285℃, free acid melting point 156-158℃.

Production methodprocess of Diclofenac sodium powder

Diclofenac sodium powder was prepared from 2, 6-dichlorodiphenylamine and chloroacetyl chloride by acylation and intramolecular Fouck alkylation

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