Factory Supply thioglycolic acid liquid CAS 68-11-1 Raw Materials

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Uses and synthesis of thioglycolic acid liquid

thioglycolic acid Raw Materials is a kind of organic acid, the chemical formula is C2H4O2S, thioglycolic acid liquid is a colorless transparent liquid, with strong unpleasant odor, miscible with water, miscible with ethanol, ether, soluble in common solvents, oxidized quickly in air, can burn and release highly toxic hydrogen sulfide gas in the case of open flame and high heat. It is mainly used as raw material of blanket finishing agent and cold ironing liquid. thioglycolic acid CAS 68-11-1 is colorless transparent liquid, industrial product is colorless to slightly yellow. Melting point - 16.5℃. Boiling point 123℃(3. 866kPa). relative density 1. 3253. Relative density 1.3253, refractive index 1.5030. thioglycolic acid CAS 68-11-1 is miscible with water, ethanol and ether.

Applications / Functions of thioglycolic acid liquid

1. thioglycolic acid Raw Materials is mainly used as raw material of blanket finishing agent and cold ironing liquid, TGA has the reaction characteristics of both hydroxy acid and sulfhydryl group, the most important reaction is the reaction with disulfide. Especially, it reacts with cystine in hair under alkaline condition, cuts the (-S-S-) bond of cystine, and generates cysteine which is easy to curl. It is mainly used as curling agent, depilatory agent, low-toxicity or non-toxicity stabilizer for polyvinyl chloride, initiator, accelerator and chain transfer agent for polymerization reaction, and metal surface treatment agent. In addition, thioglycolic acid is a sensitive reagent for the determination of iron, molybdenum, aluminum, tin, etc.; thioglycolic acid Raw Materials can also be used as polypropylene processing and molding of the crystallization of nucleating agents, as well as coatings, fibers, modifiers, carpet quick treatment agent.
2. thioglycolic acid liquid is an intermediate for the production of pharmaceuticals such as thioglycolpropanol, biotin, zinc sulfuric acid, sodium dithiobutanedioate, etc. It is also an important raw material for the synthesis of cysteine, hormonal agents, industrial disinfectants and the synthesis of sulfuric acid.
3. thioglycolic acid CAS 68-11-1 is used as the intermediate of Cefivitril, but also widely used as hair curling agent, depilatory agent, PVC low toxicity or non-toxic stabilizer, metal surface treatment agent, and polymerization reaction initiator, accelerator, and chain transfer agent.
4. Sensitive reagent for iron, molybdenum, silver, tin. thioglycolic acid CAS 68-11-1 Ammonium and sodium salts are used as curling agent, calcium salt is used as depilatory.

Physicochemical Property of thioglycolic acid liquid

thioglycolic acid CAS 68-11-1 is colorless transparent liquid, industrial products are colorless to slightly yellow, with a strong irritating odor. It is miscible with water, ethanol and ether. Perm products use thioglycolic acid to break some of the disulfide bonds in the hair to change the curvature of the hair to achieve the effect of perming and hair beauty; however, thioglycolic acid liquid has toxicity, easy to be absorbed through the skin and the respiratory tract, resulting in skin damage and allergies and other symptoms, and even affect the metabolism of the organism, and long-term exposure will cause damage to a variety of tissues and organs, and has strong mutagenicity and reproductive toxicity. Long-term exposure can cause damage to various tissues and organs, and has strong mutagenicity and reproductive toxicity. Therefore, thioglycolic acid Raw Materials need to be strictly controlled.

production methodprocess of thioglycolic acid liquid

thioglycolic acid Raw Materials are produced by the reaction of organic or inorganic sulfur-containing compounds with sodium and potassium salts of monochloroacetic acid. For example, monochloroacetic acid reacts with sodium sulfide and sulfur to generate dithiobisacetic acid, and then reduced with zinc and acid; or thiocarbamate reacts with monochloroacetic acid, and the product is hydrolyzed; monochloroacetic acid reacts with thiourea to generate isothioureidoacetic acid, and then converted into a precipitate by barium hydroxide, and then made into an aqueous solution of thioglycolic acid by sulfuric acid acid, and then 60% to 70% of solution can be obtained by evaporation with the yield of more than 70%.

1. Sodium thiosulfate and chloroacetic acid are made under the action of hydrogen sulfide and nitrogen.
2. Chloroacetic acid Sodium thiosulfate is synthesized with sodium hydroxide, and then the finished product is obtained by acid digestion, extraction and distillation.
3. Chloroacetic acid is obtained by reacting with thiourea and barium hydroxide, then by acid decomposition.

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