Metronidazole powder Raw Materials CAS 443-48-1

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Product details

Uses and synthesis of Metronidazole powder

A white or yellowish crystal or crystalline powder; It has a slight odor, bitter and salty taste. Slightly soluble in ethanol, slightly soluble in water or chloroform, and very slightly soluble in ether. Metronidazole contains nitrogen heterocyclic compound, which is alkaline and has low water solubility. According to the principle of prodrug, Metronidazole is made into potassium phosphate salt, which increases water solubility and can be used as injection. Metronidazole, also known as Metronidazole, Metronidazole, Metronidazole, and Metronidazole, is one of the nitroimidazole antibiotics, which have killing effects on anaerobic microorganisms. The metabolites generated during the reduction of Metronidazole in human body also have anti-anaerobic effects

Applications/Functions of Metronidazole powder

1. Metronidazole powder is used for the treatment of amebiasis, trichomoniasis and anaerobic infections
2. Metronidazole is mainly used to treat or prevent systemic or local infections caused by the aforementioned anaerobic bacteria, such as those in the abdominal cavity, digestive tract, female reproductive system, lower respiratory tract, skin and soft tissue, bone and joint, and is also effective for sepsis, endocarditis, meningeal infection, and colitis caused by antibiotic use. Tetanus is often treated in combination with tetanus antitoxin (TAT). It can also be used for oral anaerobic bacteria infection.
3. Metronidazole powder has been used for the treatment of vaginal trichomoniasis since 1959, and for intestinal and external amebiasis since 1970, showing high efficacy, low toxicity, and wide application. It has mutagenicity and teratogenicity in animal experiments.

Physicochemical Property of Metronidazole powder

Metronidazole white or milky crystalline powder. Melting point 158-160. Soluble in hot water, slightly soluble in ethanol, slightly soluble in water or chloroform, very slightly soluble in ether. Taste bitter and slightly salty.

Production methodprocess of Metronidazole powder

Metronidazole powder is prepared by the addition of 2-methyl-5-nitroimidazole (see 25010) to ethylene oxide.

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