Avobenzone powder Raw Materials CAS 70356-09-1

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Uses and synthesis of Avobenzone powder

There are many kinds of ultraviolet absorbers, among which phenyl ketone ultraviolet absorber is widely used, and this kind of absorber has great practical research value.Avobenzone powder belongs to phenyl ketone ultraviolet absorber, and Avobenzone CAS 70356-09-1 is also a kind of very important intermediate for organic synthesis.

Applications / Functions of Avobenzone powder

Avobenzone Raw Materials is a sunscreen. It is a topical, broad-spectrum UV-protectant that blocks UVA I, UVA II, and UVB wavelengths, thereby limiting the effects of UV on the skin.Avobenzone powder is used for the prevention of photogenic skin cancer.

Physicochemical Property of Avobenzone powder

Avobenzone CAS 70356-09-1 is a fat-soluble ingredient used in sunscreen products that absorbs all wavelengths of UVA (approximately 315 to 400 nm) and is a derivative of dibenzoylmethane (DBM). Among them, Avobenzone Raw Materials has the highest absorption rate for UVA at a wavelength of 357 nm.

Production methodprocess of Avobenzone powder

At present, the main methods for the synthesis of Avobenzone powder are:

• ① condensation addition elimination hydration method, that is, p-methoxyacetophenone and p-tert-butylbenzaldehyde through condensation, bromine addition, elimination into the alkyne, hydration to get Avobenzone powder, the yield is 58%, the method route is long, high cost, low yield;
• ② Claisen ester condensation method, that is, p-methoxyacetophenone and p-tert-butyl benzoic acid methyl ester reaction, the yield is 63.6%, the method is low cost, easy to operate, but the yield is low;
• ③ Aldehydes and ketones condensation method, that is, p-methoxyacetophenone and p-tert-butylbenzaldehyde through the condensation of alcohol, oxidation to get Avobenzone CAS 70356-09-1 , the yield is 34.6%, the method is easy to operate, high cost, low yield.

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