Aminophylline powder Raw Materials CAS 317-34-0

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Uses and synthesis of Aminophylline powder

• Aminophylline white or yellowish particles or powder. Melting point 269-274℃. Soluble in water, insoluble in ethanol or ether. Exposure to air gradually absorbs carbon dioxide gas and decomposes or theophylline. Slightly smelly, bitter taste. Aminophylline powder is a compound salt composed of theophylline and ethylenediamine. It belongs to the xanthine class of drugs, and its pharmacological action mainly comes from theophylline, which has the strongest effect on airway smooth muscle relaxation among xanthine alkaloids, and ethylenediamine can enhance its water solubility. 
• Aminophylline is suitable for the treatment of bronchial asthma, obstructive emphysema and asthmatic bronchitis. Aminophylline powder not only relaxes bronchial smooth muscle, but also can strengthen heart, diuretic, crown dilation, anti-inflammatory, antagonistic adenosine receptors, immunomodulatory and excitatory respiratory center It can also be used for the treatment of premature asphyxia, sick sinus syndrome, acute lung injury and other diseases.

Applications/Functions of Aminophylline powder

1. Aminophylline powder has the same function and use as theophylline. The presence of ethylenediamine in the molecule enhances bronchial dilation and coronary vascular action.
2. Aminophylline is mainly used for bronchial asthma and asthmatic chronic bronchitis, but also for acute cardiac insufficiency, cardiac asthma and biliary colic
3. Non-selective phosphodiesterase (PDE) inhibitors, antiepileptic drugs.

Physicochemical Property of Aminophylline powder

Aminophylline white or yellowish particles or powder. Melting point 269-274℃. Soluble in water, insoluble in ethanol or ether. Exposure to air gradually absorbs carbon dioxide gas and decomposes or theophylline. Slightly smelly, bitter taste.

Production methodprocess of Aminophylline powder

This product is a double salt of theophylline and ethylenediamine. Pour theophylline into a mixer, stir to cool, and spray into the newly distilled ethylenediamine and distilled water mixture with compressed air. After spraying, continue stirring for 10 minutes to produce Aminophylline powder.

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