Kojic Acid CAS 501-30-4

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Kojic Acid Usage and Synthesis:

Kojic acid is found in tune, it is something that people consume and is safe to use. In recent years, a large amount of patent literature has reported the use of Kojic Acid in cosmetics. Tyrosinase is the key enzyme for the production of melanin production. Triglyceride is found in soy sauce, soybean paste, and wine brewing, and can be detected in many fermented products fermented with Aspergillus oryzae. Triglycerides Triglycerides have a better tyrosinase inhibition effect than other whitening agents. It does not act on other biological enzymes in the cell and has no toxic effect on the cell. At the same time, it can enter the intercellular matrix and form intercellular colloid, which plays a role in water retention and increasing skin elasticity. At present, it has been incorporated into various cosmetic products for freckles It has been used in various cosmetics to make whitening cosmetics for freckles, age spots, hyperpigmentation and acne.

Pharmacokinetics of Kojic Acid:

An organic acid with antibacterial effect produced by aerobic fermentation of glucose at 30~32℃ by Candida trituberculatus, with the molecular structure of γ-pyrone with substituents. Among the γ-pyrone compounds existing in nature, the only well-known compounds are trehalose and maltol. The results of clinical and application tests show that tretinoin has a strong inhibitory effect on melanogenesis in human skin and is safe. It is safe, non-toxic and does not cause leukoplakia sequelae. It is a melanin-specific inhibitor that enters the skin cells and is able to complex with the cellular After entering the skin cells, it can complex with the copper ions in the cells, change the steric structure of tyrosinase, prevent the activation of tyrosinase, and thus inhibit the formation of melanin. Triglyceride-based whitening active agents have better tyrosinase activity than other whitening active agents have better tyrosinase inhibition effect.

Clinical Application of Kojic Acid:

1) Application in the field of cosmetics. In human skin, tyrosine is catalyzed by tyrosinase enzyme, and oxygen radicals undergo complex oxidation and polymerization, and finally synthesize melanin. (2) In the food processing field. Triglyceride is used as a food additive to preserve freshness and antioxidation. 3) 3. The finished product is used for the treatment of (4) In the field of agriculture. Triglyceride can be used to produce biopesticides. 5) In other fields. Tric acid can also be used as iron analysis reagent, film depigmentation agent, etc.

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