Epicatechin Powder Raw Materials CAS 490-46-0

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Uses and synthesis of Epicatechin Powder

Epicatechin Powder is the dried rhizome of buckwheat Fagopyrumdibotrys, which has the effect of clearing heat and removing toxins, expelling pus and removing blood stasis, Epicatechin CAS 490-46-0 is clinically used in the treatment of carbuncle spitting pus, asthma and coughing of lung heat and pain in the breast moth. Studies have shown that Epicatechin Raw Materials, protocatechuic acid, etc. for buckwheat antibacterial, anti-inflammatory, cough suppressant main components.

Buckwheat ethanol extract of epicatechin content of 65% to 70%, Epicatechin CAS 490-46-0 become an important indicator of buckwheat content determination. In addition, Epicatechin Powder also has a preventive effect on cardiovascular and cerebrovascular, as well as preventing tumors, with antioxidant effects .

Epicatechin Raw Materials can inhibit LPS-induced inflammatory response of RAW264.7 cells, and its anti-inflammatory effect is related to the inhibition of cellular inflammatory factors NO, TNF-α, IL-1 and IL-6 production, down-regulation of iNOS protein expression, mediated activation of the MARK signaling pathway p38, ERK1/2 and the regulation of the expression of JNK protein.

Applications / Functions of Epicatechin Powder

• Epicatechin Raw Materials are used for content determination/identification/pharmacological experiments.
• Pharmacological effects:Epicatechin Powder can prevent cardiovascular disease, cancer, and antioxidant effects.

Physicochemical Property of Epicatechin Powder

Derived from the peeled branches of Acacia catechu (L.F.) Willd, family Leguminosae.

Production methodprocess of Epicatechin Powder

Through the one-way test method, the F-test and the new complex polar deviation method (SSR method) comparison, has determined the ethanol concentration, extraction temperature, material-liquid ratio, extraction time of the approximate range; and then through the four-factor, three-level orthogonal test, to get the optimized extraction process for the ethanol volume fraction of 60%, the extraction temperature of 20 ℃, the material-liquid ratio (g/mL) 1:18, the extraction time of 30min, to obtain the gold buckwheat (-) the average extraction rate of epicatechin-like active substances reached 2.5%.

The process is simple and reasonable, and can be applied to Epicatechin CAS 490-46-0 monomer industrialization of pre-production.

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