Formamide CAS 75-12-7

CAS: 75-12-7

MF: CH3NO

Specification​: 99% min

Sample: Formamide Liquid

Brand: Global Chemical

Appearance: Liquid

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Formamide Usage and Synthesis:

Formamide is a formic acid-derived amide with the molecular formula HCONH2. It is a colorless and odorless oily liquid with a slight ammonia odor when it contains impurities. It is miscible with water and has an odor similar to that of ammonia. . It is insoluble in ether and chlorinated solvents, slightly soluble in benzene, miscible with water, methanol, ethanol, acetic acid, acetone, dioxane, ethylene glycol, phenol and low grade esters. Mainly used It is mainly used in the production of sulfonamides, synthetic vitamins and as a softening agent for paper and fiber. Pure formamide can dissolve many ionic compounds that are insoluble in water and is therefore also used as a solvent. It is also used as a solvent. This product should be stored in a cool and dry place under seal. Keep sealed, avoid contact with water and store in a cool, ventilated place. This product can dissolve casein but not albumin It can dissolve casein but not albumin. It can also dissolve casein, glucose, corn protein, gelatin, animal glue, resin, starch, lignin, acetate fiber, nylon and some inorganic salts: copper, lead, zinc Tin, cobalt, iron, aluminum and nickel chloride, some sulfates, nitrates.

Pharmacokinetics of Formamide:

Formamide can undergo a variety of reactions, including dehydration, deCO, introduction of amino groups, introduction of acyl groups, and cyclization, in addition to reactions involving three hydrogens. Cyclization For example. Diethyl malonate is cyclized with formamide to give 4,6-dihydroxypyrimidine, an intermediate of vitamin B4. The cyclization of o-aminobenzoic acid with amide gives the intermediate of anti-arrhythmic often coke The intermediate of quinazoline-4. 3-amino-4-ethoxycarbonyl pyrazole was cyclized with formamide to obtain allopurinol, an inhibitor of xanthine oxidase. The cyclization of ethylenediaminetetraacetic acid with formamide yields to the anticancer drug ethyleneimine. The cyclization of methyl ethyl methoxymalonate with formamide yields disodium 5-methoxy-4,6-dihydroxypyrimidine, an intermediate of sulfonamides. Formamide can strongly corrode Therefore, care should be taken when storing and transporting.

Clinical Application of Formamide:

Formamide has active reactivity and special solubility, and can be used as raw material for organic synthesis, paper treatment agent, softener for fiber industry, softener for animal glue, and It is also used as an analytical reagent to determine the amino acid content in rice. In organic synthesis, the use of medicine is the majority, in pesticides, dyes, pigments, spices, additives also have Many uses. It is also an excellent organic solvent, mainly used in the spinning of acrylonitrile copolymers and ion exchange resins, as well as the anti-static coating or conductive coating of plastic products. etc. Because formamide can dissolve inorganic salts and proteins with high dielectric constant, it can be used in electrolysis and electroplating industry, as well as the reaction solvent of organic synthesis and refining solvents. It is also used as a reaction solvent and refining solvent in organic synthesis. In addition, formamide is also used as raw material for medicine, dyestuff, spices, etc., treatment agent for paper, softener for fiber industry and softener for animal glue, etc.