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  • Obeticholic Acid powder Raw Materials CAS 459789-99-2

    • Obeticholic Acid powder Raw Materials CAS 459789-99-2
    • Obeticholic Acid powder Raw Materials CAS 459789-99-2
    • Obeticholic Acid powder Raw Materials CAS 459789-99-2
    • Obeticholic Acid powder Raw Materials CAS 459789-99-2 workshop
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    • Obeticholic Acid powder Raw Materials CAS 459789-99-2

    Product Overview:

    Obeticholic Acid powder, also known as 6-ethyl channedeoxycholic acid, is a novel derivative of channedeoxycholic acid (CDCA) in human primary bile acids. Obeticholic acid powder is a natural ligand of farnesate derivative X receptor (FXR). Obeticholic Acid is a farnesol X receptor agonist. Obeticholic acid indirectly inhibits cytochrome 7A1 (CYP7A1) gene expression by activating farnesol X receptor. Since CYP7A1 is a rate-limiting enzyme for cholic Acid biosynthesis, Obeticholic Acid can inhibit cholic acid synthesis for the treatment of primary biliary cirrhosis and non-alcoholic fatty liver disease.

    Obeticholic Acid powder Raw Materials CAS 459789-99-2 Attributes

    CAS:459789-99-2

    MF:C26H44O4
    Obeticholic Acid powder

    MW:420.63

    EINECS:810-245-2

    Specification:Obeticholic Acid powder

    Sample:Obeticholic Acid powder

    Brand:Obeticholic Acid powder

    Appearance: powder

    Storage: Cool Dry Place

    Brand: chemical Raw Materials

    Shelf Life: 2 Years

    Test Method: HPLC

    Obeticholic Acid powder Raw Materials CAS 459789-99-2 Details

    Uses and synthesis of Obeticholic Acid powder

    Obeticholic Acid powder, also known as 6-ethyl channedeoxycholic acid, is a novel derivative of channedeoxycholic acid (CDCA) in human primary bile acids. Obeticholic acid powder is a natural ligand of farnesate derivative X receptor (FXR). Obeticholic Acid is a farnesol X receptor agonist. Obeticholic acid indirectly inhibits cytochrome 7A1 (CYP7A1) gene expression by activating farnesol X receptor. Since CYP7A1 is a rate-limiting enzyme for cholic Acid biosynthesis, Obeticholic Acid can inhibit cholic acid synthesis for the treatment of primary biliary cirrhosis and non-alcoholic fatty liver disease.

    Obeticholic Acid powder

    Applications/Functions of Obeticholic Acid powder

    1. Obeticholic Acid powder (OCA) is a potent agonist of synthetic modified bile acids and farnesoid X nuclear receptor (FXR) for the treatment of liver diseases, including primary cholangitis.
    2. Since CYP7A1 is a rate-limiting enzyme for cholic Acid biosynthesis, Obeticholic Acid can inhibit cholic acid synthesis for the treatment of primary biliary cirrhosis and non-alcoholic fatty liver disease.

    Obeticholic Acid

    Physicochemical Property of Obeticholic Acid powder

    Obeticholic Acid

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