Glabridin Powder CAS 59870-68-7

CAS: 59870-68-7

MF: C20H20O4

Specification​: 99% min

Sample: Glabridin Powder

Brand: Global Chemical

Appearance: Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Glabridin Usage and Synthesis:

Glabridin is a flavonoid extracted from a precious plant called Glycyrrhiza glabra, which is a white powder with high content. It is insoluble in water and soluble in butylene glycol, propylene glycol and other organic solvents. Because of its powerful whitening effect, it is known as "whitening gold", which can eliminate free radicals and melanin at the bottom of the muscle, and is a whitening and It is the holy grail of skin whitening and anti-aging. Some experts have found that Glabridin has an appetite suppressing effect, it can reduce fat without losing weight, and it has a strong anti-bacterial, anti-UV-induced hair loss effect. It has strong anti-bacterial, UV-induced inflammation, hyperpigmentation and skin roughness effects. After repeated tests, Glycyrrhizin is mainly used in cosmetic applications by the following effects 1: whitening, and Inhibition of melaninogen; 2: anti-inflammatory effect 3: antioxidant effect 4: antibacterial.

Pharmacokinetics of Glabridin:

Glabridin is one of the major flavonoid components of Glycyrrhiza glabrida. It shows a strong anti-free radical oxidation effect in the cytochrome P450/NADPH oxidation system and can significantly inhibit free radicals generated during metabolic processes in the body and prevent oxidation-sensitive biomass. It can significantly inhibit the free radicals generated during the metabolic process in the body and prevent the damage of oxidation-sensitive biomolecules (LDL, DNA) and cell walls by free radicals. oxidative damage. Thus, it can prevent certain pathological changes related to free radical oxidation, such as atherosclerosis, cellular aging, etc. In addition, Glycyrrhizin also has certain hypolipidemic and hypotensive effects. In addition, Glycyrrhiza glabra has certain hypolipidemic and hypotensive effects. The yellow color of licorice extract is mainly caused by the flavonoids in it, but it also has other effects. The flavonoid component of licorice root has anti spasmolytic effect. Licorice flavonoids are the main flavonoid components and have anti-inflammatory activity. These flavonoids have antioxidant and hepatoprotective effects.

Clinical Application of Glabridin:

Glabridin is a compound extracted from Glycyrrhiza glabra (root) with cytotoxic, antibacterial, estrogenic, and antiproliferative properties. Glabridin is isolated from licorice flavonoids Licorice flavonoids are extracted from the roots of specific species of licorice plants (e.g., Ural licorice, bloated fruit licorice, light fruit licorice, etc.). It is natural, pollution-free and has no side effects on human body. It is known as "whitening gold" because of its efficient ability to inhibit reactive oxygen species and melanin. The second is that the price of a single gram of Glycyrrhizin is comparable to gold, and only a few brands dare to use it as a whitening ingredient. Therefore, it is used as the ingredient of various cosmetics and medical care products (such as facial creams, lotions, body washes, etc.). It can be made into whitening creams, and there are already patented products of this kind on the market.