Good Price L-5-MTHF Ca powder Raw Materials CAS 151533-22-1

Product name:L-5-MTHF Ca powder

CAS:151533-22-1

MF:C20H27CaN7O6

MW:501.56

EINECS:691-636-3

Specification:L-5-MTHF Ca powder

Sample:L-5-MTHF Ca powder Avaliable

Appearance:white powder

Storage: Cool Dry Place

Brand:Global ASAP Nutrition Factory

Shelf Life: 2 Years

Test Method: HPLC

Uses and synthesis of L-5-MTHF Ca powder

L-5-methyltetrahydrocalcium folate, also known as L-5-MTHF Ca powder, is a chemical intermediate with the molecular formula C20H23CaN7O6 and molecular weight 497.5179. L-5-MTHF Ca is a calcium salt of L-5-methyltetrahydrofolate, a member of the folate family of vitamins (vitamin B9, folate), which is a coenzyme form of folate. L-5-methyltetrahydrofolate (5-mthf) is a naturally occurring salt-forming methyl derivative form of folate, 5-mthf is also known as L-methylfolate, L-5-MTHF Ca is the most biologically active and functional form of folate, and is more easily absorbed than ordinary folate.

Functions of L-5-MTHF Ca powder

Cell division and growth: DNA synthesis is the basis of cell division, so folic acid is essential for the normal division and growth of cells, especially rapidly dividing cells such as red blood cells, white blood cells, intestinal cells, skin cells, etc. Folic acid deficiency may cause cell division disorders and affect the normal function of tissues and organs.

Erythropoiesis: Folic acid is an essential vitamin for the maturation of red blood cells. Folic acid deficiency can lead to megaloblastic anemia, which is manifested by increased red blood cell volume and decreased oxygen carrying capacity, causing anemia symptoms such as fatigue, dizziness, and shortness of breath.

Homocysteine ​​metabolism: Folic acid participates in the metabolic pathway of homocysteine ​​conversion to methionine. Folic acid deficiency can lead to elevated homocysteine ​​levels, and hyperhomocysteinemia is considered a risk factor for cardiovascular disease, neurodegenerative diseases, pregnancy complications, and other diseases. Folic acid supplementation helps lower homocysteine ​​levels and maintain cardiovascular health.

Neurotransmitter synthesis: Folic acid is involved in the synthesis of neurotransmitters (such as serotonin, dopamine, and norepinephrine). These neurotransmitters play an important role in mood regulation, sleep, cognitive function, etc. Folic acid deficiency may be associated with depression, anxiety, and decreased cognitive function.

Advantages of L-5-MTHF Ca powder

Higher bioavailability: Compared with synthetic folic acid, L-5-MTHF Ca can be directly used by the human body without multiple enzymatic conversions. This means that it is more easily and quickly absorbed into the blood circulation and participates in physiological metabolism.

Bypassing the MTHFR gene mutation problem: The conversion of synthetic folic acid into the active form of L-5-MTHF requires a key enzyme, methylenetetrahydrofolate reductase (MTHFR). However, a considerable number of people (especially certain ethnic groups) carry MTHFR gene mutations, which leads to reduced activity of this enzyme and affects the conversion efficiency of synthetic folic acid. L-5-MTHF Ca directly provides active form of folic acid without further conversion by the MTHFR enzyme, so it is more suitable for people with MTHFR gene mutations.

Safer choice: Some studies have shown that the accumulation of unmetabolized synthetic folic acid in the body may bring potential health risks, such as masking vitamin B12 deficiency and may be associated with an increased risk of certain cancers (research is still ongoing). L-5-MTHF Ca, as the active form, is closer to the body's natural metabolic pathway and is considered safer, especially suitable for long-term supplementation.