Best Price Supplements Food Grade Calcium Gluconate Powder

Product name:Calcium gluconate powder

CAS:299-28-5

MF:C12H22CaO14

MW:430.37

EINECS:206-075-8

Specification:99% min Calcium gluconate powder

Sample:Calcium gluconate powder Avaliable

Appearance:white powder

Storage: Cool Dry Place

Brand:Global ASAP Nutrition Factory

Shelf Life: 2 Years

Test Method: HPLC

Uses and synthesis of Calcium gluconate powder.

Calcium gluconate powder is a calcium salt of gluconic acid. It is a white crystalline or granular powder with a melting point of 201℃, odorless and tasteless, soluble in cold water and easily soluble in hot water. As an important organic Calcium, Calcium gluconate is mainly used as calcium fortification and nutritive agent, buffer, curing agent, and chelating agent in food, and has a broad application prospect. Calcium gluconate powder belongs to organic calcium acids and is mainly used for the prevention and treatment of calcium deficiencies (such as osteoporosis, osteoplasia, rickets, and calcium supplementation in children, pregnant and lactating women, postmenopausal women, and the elderly), as well as tetany caused by acute hypocalcemia, alkalosis, and hypoparathyroidism.

What are the health benefits of calcium gluconate?

Rapid correction of acute hypocalcemia: Intravenous calcium gluconate can quickly increase blood calcium levels, effectively relieve symptoms caused by acute hypocalcemia, such as tetany, convulsions, laryngeal spasms, etc., and save patients' lives.

Supplement calcium and prevent calcium deficiency: Oral or injected calcium gluconate can provide calcium to the body, prevent and treat chronic calcium deficiency, such as osteoporosis, rickets, etc., and maintain bone and tooth health.

Fight against hyperkalemia, hypermagnesemia and fluorosis: In certain cases of poisoning and electrolyte disorders, calcium gluconate can play a rescue and antagonistic role and assist in treatment.

Relatively mild, higher intravenous safety: Compared with other calcium salt injections, calcium gluconate injection is less irritating, has higher intravenous safety, and has a lower risk of vascular irritation and tissue necrosis.

How to use calcium gluconate correctly？

Calcium gluconate for intravenous injection: It is a prescription drug and must be used under the guidance of a doctor and strictly follow the doctor's instructions:

Indications: It is only used to treat emergency situations such as acute hypocalcemia, hyperkalemia, hypermagnesemia, fluoride poisoning, calcium channel blocker poisoning, and other situations where the doctor believes that intravenous calcium supplementation is necessary. It cannot be used for daily calcium supplementation or preventive calcium supplementation.

Route of administration: It must be injected slowly intravenously. Arterial injection or intramuscular injection is strictly prohibited to avoid serious adverse reactions. The injection speed should be slower for children and the elderly.

Injection speed and concentration: Strictly control the injection speed and concentration to avoid too fast and too concentrated. Generally, the recommended injection speed for adults is no more than 2mL per minute (based on 10% calcium gluconate injection), and it is slower for children. Excessive concentration may increase the risk of vascular irritation and calcification.

ECG monitoring: During intravenous injection, ECG monitoring should be performed to closely observe changes in heart rate and heart rhythm. If arrhythmia, bradycardia, etc. occur, the injection should be stopped immediately and appropriate treatment should be taken.

Injection site management: Choose a thick vein to avoid repeated injections at the same site to prevent drug extravasation. Observe the injection site after injection. If there is inflammatory reaction or nodules such as redness, swelling, heat and pain, treat it in time.

Monitoring blood calcium: When calcium gluconate is injected intravenously for a long time, blood calcium levels should be monitored regularly to prevent hypercalcemia.

Oral calcium gluconate tablets/oral solution: As an over-the-counter drug or dietary supplement, it can be used under the guidance of a pharmacist or doctor, and pay attention to the following matters:

Indications: Mainly used for the prevention and treatment of chronic calcium deficiency, such as insufficient dietary calcium intake, osteoporosis, rickets in children, calcium supplementation for pregnant and lactating women, etc. It is not suitable for the emergency treatment of acute hypocalcemia.

Dosage: Read the product instructions carefully and take it according to the recommended dosage. The recommended daily intake of elemental calcium is 800-1200mg for adults, and children, adolescents, pregnant women, and lactating women have higher requirements. The dosage of calcium gluconate tablets or oral solution should be converted according to its elemental calcium content. Do not take in excess.

Time of taking: Oral calcium gluconate tablets can be taken after meals to reduce gastrointestinal discomfort. Oral liquid dosage form can be taken directly.

Pay attention to interactions with other drugs: If you are taking other drugs, especially digoxin drugs, tetracycline antibiotics, etc., you should consult a doctor or pharmacist to find out whether you need to adjust your medication plan.

Preparation method of calcium gluconate.

Reaction of gluconic acid with calcium hydroxide: This is the most commonly used method. React an aqueous solution of gluconic acid with calcium hydroxide (lime milk). The reaction equation is as follows:

2C₆H₁₂O₇ + Ca(OH)₂ → Ca(C₆H₁₁O₇)₂ + 2H₂O

Gluconic acid reacts with calcium hydroxide to produce calcium gluconate and water. The reaction solution is filtered, concentrated, crystallized, washed, dried, and other steps to obtain the finished calcium gluconate.

Reaction of gluconic acid with calcium carbonate: Calcium carbonate can also be used as a calcium source to react with an aqueous solution of gluconic acid. The reaction equation is as follows:

2C₆H₁₂O₇ + CaCO₃ → Ca(C₆H₁₁O₇)₂ + H₂O + CO₂↑

Gluconic acid reacts with calcium carbonate to produce calcium gluconate, water, and carbon dioxide. The carbon dioxide escapes as a gas and the subsequent processing steps are similar to the calcium hydroxide method.