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Imatinib mesylate powder Raw Materials CAS 220127-57-1
Product Overview:
The chemical name of Imatinib mesylate powder is 4-(4-methyl-1-piperazine) methyl-N-4-methyl-3-4 -(3-pyridine) -2-pyrimidine aminophenyl-benzoamide mesylate, the molecular formula is C29H31N7O·CH4SO3, and the molecular weight is 589.7. Imatinib mesylate can inhibit Bcr-Abl tyrosine kinase at the cellular level in vivo and in vitro, selectively inhibit proliferation and induce apoptosis of Bcr-Abl positive cell lines, Ph chromosome positive chronic myelogenous leukemia and acute lymphoblastic leukemia patients.
Imatinib mesylate powder Raw Materials CAS 220127-57-1 Attributes
MF:C30H35N7O4S
MW:589.71
EINECS:606-892-3
Specification:Imatinib mesylate powder
Sample:Imatinib mesylate powder
Brand:Imatinib mesylate powder
Appearance: powder
Storage: Cool Dry Place
Brand: chemical Raw Materials
Shelf Life: 2 Years
Test Method: HPLC
Imatinib mesylate powder Raw Materials CAS 220127-57-1 Details
Uses and synthesis of Imatinib mesylate powder
The chemical name of Imatinib mesylate powder is 4-(4-methyl-1-piperazine) methyl-N-4-methyl-3-4 -(3-pyridine) -2-pyrimidine aminophenyl-benzoamide mesylate, the molecular formula is C29H31N7O·CH4SO3, and the molecular weight is 589.7. Imatinib mesylate can inhibit Bcr-Abl tyrosine kinase at the cellular level in vivo and in vitro, selectively inhibit proliferation and induce apoptosis of Bcr-Abl positive cell lines, Ph chromosome positive chronic myelogenous leukemia and acute lymphoblastic leukemia patients.
Applications/Functions of Imatinib mesylate powder
- Imatinib mesylate powder also inhibited tyrosine kinases of platelet-derived growth factor (PDGF) receptors, stem cell factor (SCF) receptors, and c-Kit receptors, thereby inhibiting PDGF and stem cell factor-mediated cell behavior.
- Imatinib mesylate can inhibit Bcr-Abl tyrosine kinase at the cellular level in vivo and in vitro, selectively inhibit proliferation and induce apoptosis of Bcr-Abl positive cell lines, Ph chromosome positive chronic myelogenous leukemia and acute lymphoblastic leukemia patients.
Physicochemical Property of Imatinib mesylate powder
