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Pharmaceutical material and intermeidates telmisartan
Product Overview:
Telmisartan is a new type of antihypertensive drug and a specific angiotensin II receptor (ATⅠ type) antagonist used to treat essential hypertension. It replaces the angiotensin II receptor and binds with high affinity to the ATⅠ receptor subtype (known angiotensin II action site). Telmisartan has no agonist effect at any part of the ATⅠ receptor site, and selectively binds to the ATⅠ receptor, and the binding effect is long-lasting.
Pharmaceutical material and intermeidates telmisartan Attributes
CAS:144701-48-4
MF:C33H30N4O2
MW:514.62
EINECS:620-494-7
Specification: 99% min telmisartan powder
Sample:telmisartan powder
Packaging:1kg/bag, 25kg/drum
Brand:Global ASAP Nutrition Factory
Appearance:white
Shelf Life: 2 Years
Test Method: HPLC
Pharmaceutical material and intermeidates telmisartan Details
telmisartan powder Usage and Synthesis.
Telmisartan is an orally effective, specific angiotensin II receptor (AT1 type) antagonist. This product can selectively bind to the AT1 receptor, and has a long-lasting effect, which can increase the level of angiotensin II.
It is mainly used to lower blood pressure. It can also be used for patients (aged 55 years and above) who are at high risk of serious cardiovascular events and cannot receive angiotensin converting enzyme (ACE) inhibitor treatment to reduce the risk of myocardial infarction, stroke or death caused by cardiovascular disease.
Telmisartan can reduce aldosterone levels, but does not inhibit human plasma renin activity or block ion channels, and does not inhibit angiotensin converting enzyme (ACE, kininase II). Therefore, the use of telmisartan will not enhance bradykinin-mediated adverse reactions.
Uses of telmisartan powder.
1. Lowering blood pressure: Telmisartan tablets are angiotensin receptor blockers. Taking this drug can dilate blood vessels and reduce the pressure in peripheral blood vessels, which can lower blood pressure and is effective in treating hypertension.
2. Improving myocardial function: Taking Telmisartan tablets can also improve myocardial stenosis, increase myocardial blood supply and oxygen supply, reduce the risk of cardiovascular disease, and help prevent acute myocardial infarction. Because the severity of each patient's condition is different, the drug treatment when taking Telmisartan tablets will also be different, and the specific dosage needs to be followed according to the doctor's advice.
Function of telmisartan.
Telmisartan is mainly used to lower blood pressure. It can also be used for patients who are at high risk of serious cardiovascular events and cannot receive angiotensin-converting enzyme (ACE) inhibitor treatment to reduce their risk of myocardial infarction, stroke or death due to cardiovascular disease.
Pharmacological Action of Bulk telmisartan.
