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Product details
p-Toluenesulfonyl chloride Raw Materials, as a kind of fine chemicals, are widely used in dyestuff, pharmaceutical and pesticide industries. In the dyestuff industry, p-Toluenesulfonyl chloride Powder is mainly used as intermediates for the manufacture of disperse, ice-dyed and acid dyestuffs. p-Toluenesulfonyl chloride Powder is mainly used for the production of sulfadiazine, metsulfometuron and so on in the pharmaceutical industry, and is mainly used for the production of methylsulfonylmethane, sulfoxaflutole, spermacetiramine and so on in the pesticide industry. With the continuous development of dyestuff, pharmaceutical and pesticide industries, the demand for this product is growing internationally, especially in Europe and the United States, and the market prospect is broad.
p-Toluenesulfonyl chloride Powder is white flaky crystal with melting point of 69-71°C. It is an important intermediate for organic synthesis of drugs, mainly used in the synthesis of aminosulfonyl chloramphenicol, chloramine-T, methylsulfonylmethoxymethane, etc. It is also used in the production of p-Toluenesulfonyl chloride Powder.
p-Toluenesulfonyl chloride Powder is the intermediate of disperse dye, ice dye and acid dye. It is also used in the production of the drug Methylsulfonylmethane.
Applications / Functions of p-Toluenesulfonyl chloride Powder
p-Toluenesulfonyl chloride Powder properties and stability
p-Toluenesulfonyl chloride CAS 98-59-9 White flaky crystal. Melting point 71℃. Boiling point 151.6℃(1.67kPa), 145-146℃(2.0kPa). Soluble in alcohol, ether and benzene, insoluble in water.
Production method of p-Toluenesulfonyl chloride Powder
The traditional processes of p-Toluenesulfonyl chloride CAS 98-59-9 are mainly the following two:
First, toluene and excess chlorosulfonic acid under the low temperature of direct chlorination, this method of production contains high o-toluenesulfonyl chloride, p-Toluenesulfonyl chloride for its by-products, and the two are difficult to separate, energy consumption;
Second, toluene and chlorosulfonic acid in the presence of certain salts and a certain temperature directly with excess chlorosulfonic acid chlorination system, the method, although the proportion of the product of p-toluenesulfonyl chloride is higher than the method of purification than the method is easy, low energy consumption, but due to the reaction temperature is relatively high, the separation of sulfonated oil containing sulfone is higher, the use of value is low, and the actual total yield is only about 70%. In addition, both methods have high consumption of raw material chlorosulfonic acid, and the waste sulfuric acid generated from the production is too dilute, which is not conducive to industrial utilization and treatment. There are also reports on the improvement of the method, first of all, to make the reaction mixture of p-toluenesulfonyl chloride in certain conditions to fully crystallize out, and to make the crystalline particles increase, the use of not hydrolysis but direct filtration method to make p-toluenesulfonyl chloride from the mixture of separation, but at present in the selection of the industrialization of the device has some difficulties, and the investment is large. Improvement of the process: A suitable catalyst was selected, as well as other optimal process conditions.
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