Scopolamine hydrobromide powder Raw Materials CAS 114-49-8

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Uses and synthesis of Scopolamine hydrobromide powder

Scopolamine hydrobromide powder CAS No. 114-49-8, molecular formula :C17H22BrNO4, molecular weight :384.2649. Colorless transparent crystalline or white crystalline powder, odorless, bitter taste, slightly weathered in dry air. Scopolamine hydrobromide CAS 114-49-8 Soluble in water, acidic in aqueous solution, soluble in ethanol, slightly soluble in chloroform, insoluble in ether. Scopolamine hydrobromide Raw Materials are primarily used as anticholinergics, can be used to block parasympathetic nerves, and can also be used as central nervous system preparations.

Applications/Functions of Scopolamine hydrobromide powder

1. Anticholinergic drugs. Scopolamine hydrobromide powder is one of the most pharmacological alkaloids available and can be used to block parasympathetic nerves or as a preparation for the central nervous system. The effect is similar to that of belladonna base, but stronger and shorter.
2. Scopolamine hydrobromide CAS 114-49-8 can be used for anesthesia, analgesia, cough, asthmatic relief, effective against motion sickness, and can also be used to control stiffness and tremor of Parkinson's disease. Biochemical research.

Physicochemical Property of Scopolamine hydrobromide powder

Colorless transparent crystalline or white crystalline powder, odorless, bitter taste, slightly weathered in dry air. Soluble in water, aqueous solution is acidic, soluble in ethanol, slightly soluble in chloroform, insoluble in ether.

Production methodprocess of Scopolamine hydrobromide powder

Scopolamine hydrobromide Raw Materials were extracted from the flower. The Chinese herbal anesthetic Yangjinhua preparation, originated from the famous doctor Huatuo's Ma Fei SAN in the 2nd century AD, its active ingredient is scopolamine. Percolate the coarse powder with ethanol at 50℃ until the exudate is almost free of alkaloids.

The extracted extract was extracted with sulfuric acid, the extracted solution was added with sodium carbonate to prepare pH9-10, and the extracted solution was extracted with chloroform, and the extracted solution was distilled to recover the chloroform to obtain the total alkaloids, and then separated into salt to obtain the product. The total yield was 0.15%.

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