Factory Supply gamma-cyclodextrin Powder CAS 17465-86-0 Raw Materials

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Uses and synthesis of gamma-cyclodextrin Powder

gamma-cyclodextrin Powder Molecular Formula is C48H80O40, molecular weight is 1297.1248, CAS registry number is 17465-86-0, white powder, spice modifier, stabilizer.

gamma-cyclodextrin CAS 17465-86-0 has a cavity in the center of the ring structure, and inside there is -CH- and glucoside bonded oxygen atoms, which is sulfur-hydraulic, and glucose 2-position, 3-position, and 6-position -OH group is hydrophilic, and it can be complexed to other molecules into an encapsulated substance by weak van der Waals force. There are many substances that can be encapsulated by gamma-cyclodextrin CAS 17465-86-0, including rare gases, halogens, dyes, spices, drugs, food, pesticides and preservatives. After bonding, its stability, volatility, solubility and reactivity are improved.

gamma-cyclodextrin Raw Materials was discovered by Villers in 1891, the beginning of this century and the isolation of successful α and β cyclodextrins. 1972-1973 production of cyclodextrin enzyme (i.e., cyclodextrin glucosyltransferase, referred to as CGT-ase) bacteria were found, in particular, the alkalophilic bacteria, for the large-scale production of cyclodextrins The discovery of CGT-ase, especially the alkalophilic bacteria, is of great importance for the large-scale production of cyclodextrins.

Applications / Functions of gamma-cyclodextrin Powder

Applications / Functions of gamma-cyclodextrin Powder: Carrier; Flavor modifier; Stabilizer.

gamma-cyclodextrin Powder has a cavity in the center of the ring structure, with -CH-oxygen atoms bound to glucoside, which is sulfur-hydrogen, and the -OH groups at the 2-position, 3-position and 6-position of glucose are hydrophilic, which can complex other molecules into an adduct through weak van der Waals force. There are many substances that can be encapsulated by gamma-cyclodextrin Raw Materials, including rare gases, halogens, dyes, spices, drugs, food, pesticides and preservatives. After encapsulation, their stability, volatility, solubility and reactivity are improved. This special effect of cyclodextrin makes gamma-cyclodextrin CAS 17465-86-0 an encapsulated material with a wide range of application value.

• 1.gamma-cyclodextrin CAS 17465-86-0 in the pharmaceutical industry use cyclodextrin can be used with the drug to generate the inclusion material (encapsulation), can make (1) unstable drug stabilization; (2) chaotropic, adhesive or liquid drug powder; (3) insoluble or insoluble drug solubility (solubilizing) and so on.
• 2.gamma-cyclodextrin Raw Materials in the pesticide industry in the use of cyclodextrin package stabilization, some pesticides can be resistant to storage and improve insecticidal efficacy.
• 3.gamma-cyclodextrin Raw Materials in the food industry cyclodextrin used in the food industry, has the following effects: (1) the elimination of special odor and masking; (2) the food organization structure of the enhancement and improvement; (3) the reduction of bitterness and astringent taste and removal; (4) antioxidant effect; (5) the maintenance of the flavor and the optimization.
• 4. gamma-cyclodextrin Powder is used in daily-use chemical industry. Cyclodextrin can also be used as emulsifier and quality improver in the manufacture of cosmetics. It also has deodorization (such as deodorant) and antiseptic effects, and can be used in the manufacture of toothpaste and tooth powder.
• 5.gamma-cyclodextrin CAS 17465-86-0 can be used as a treatment agent for oily wastewater in environmental protection. The aqueous solution of cyclodextrin is used to clean oil tanks, and its waste liquid can be recycled and treated to obtain fuel oil.
• 6.gamma-cyclodextrin Powder Uses in ChemistryCyclodextrin is a valuable chemical reagent. When it exists, the fluorescence intensity of the fluorescent pigment will increase significantly, so it can be used for protein, amino acid analysis; it can also be used to separate the long-chain organic compounds, racemates and so on. In addition, adsorbents made from cyclodextrins can be used as adsorbents for chromatographic analysis. This reaction can also be carried out in benzene (or acetonitrile), although potassium cyanide is insoluble in benzene, but if you add 18-crown-6, not only can the reaction take place, and the yield can be as high as 95%.Toxicity of 18-crown-6: Oral LD50 for rats is 300mg/kg.Irritating to the eyes and skin.Toxicity of gamma-cyclodextrin CAS: Oral LD50 is 300mg/kg.To the eyes and skin.

gamma-cyclodextrin CAS 17465-86-0 Uses in Chemistry Cyclodextrin is a valuable chemical reagent. When it exists, the fluorescence intensity of fluorescent pigment will increase significantly, so it can be used for the analysis of protein and amino acid; it can also be used to separate long-chain organic compounds and racemates. In addition, the adsorbent made of cyclodextrin can be used as adsorbent for chromatographic analysis. It can also be used as complexing agent, enzyme activity research, tissue culture agent. This product should be sealed and stored in a dry place.

gamma-cyclodextrin Powder properties and stability

gamma-cyclodextrin CAS 17465-86-0 is a non-reducing cyclic sugar consisting of eight alpha-1,4-bonded D-glucopyranose units cyclized together. Practically odorless, white or almost white crystalline solid.

Production method of gamma-cyclodextrin powder

1. gamma-cyclodextrin CAS 17465-86-0 was discovered by Villers in 1891, and α and β cyclodextrins were successfully isolated at the beginning of this century.1972-1973, the discovery of the bacteria that produce cyclodextrin enzymes (i.e., cyclodextrin glucanotransferase, abbreviated as CGT-ase), especially the basophilic bacteria, was of great significance to the large-scale production of cyclodextrins. Cyclodextrin is of great significance. Cyclodextrin can be obtained from the processed starch of potato, corn and wheat by the following process: starch suspension [liquefied at 70-80°C] [reacted with ethanol at 60°C], heat deactivation, filtration, concentration and drying.
2. gamma-cyclodextrin Powder is obtained by the action of cyclic maltodextrin glucosyltransferase (CGTase, EC 2.4.1.19) on hydrolyzed starch, which is then purified by one of the following methods: bradcyclodextrin is precipitated with a complex of a macrocyclic compound, followed by n-decane extraction, and then vapor extraction of the solvent; the purified mother liquor from the solution containing bradcyclodextrin is purified with Crystallization was obtained from the purified mother liquor containing Brachydextrin by chromatographic separation by ion exchange or gel filtration; and by membrane separation by ultrafiltration and reverse osmosis.

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