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Sunitinib powder, also known as Sunitinib malate or Sutan, is a multi-target tyrosine kinase inhibitor that acts on multiple targets such as PDGFRα, PDGFRβ, VEGFR1, and RET, inhibiting the dysregulation of RTKs expression in tumor cells and anti-tumor angiogenesis. Metabolically dependent cytochrome P450 enzyme. Sunitinib is indicated for patients with gastrointestinal stromal tumors that are resistant to or have progressed after treatment with imatinib, or for the treatment of renal cell carcinoma.
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