Diethyl malonate liquid Raw Materials CAS 105-53-3

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Uses and synthesis of Diethyl malonate liquid

Diethyl malonate liquid Diethyl malonate liquid has a sweet ether odor. It is miscible with alcohol and ether, soluble in organic solvents such as chloroform and benzene. Slightly soluble in water. Malonic acid and its derivatives are widely used in pharmaceutical, flavoring, food additives, polyester and other industries, and are important fine chemical raw materials and intermediates. Diethyl malonate is widely used in the synthesis of barbianic acid, amino acids, vitamins B1, B2 and B6, as a sleep aid and phenylbutazone. Diethyl malonate is an important fine chemical raw material. As the methylene hydrogen in its molecule is easily replaced by a variety of groups, a variety of important derivatives can be generated. Diethyl malonate liquid is widely used in various chemical production fields. Including food, medicine, pesticides, industrial dyes, liquid crystal materials and other industries.

Applications/Functions of Diethyl malonate liquid

1. Diethyl malonate liquid is an important intermediate for the preparation of 2-amino-4, 6-dimethoxy-pyrimidine, which can be used in the preparation of sulfonylurea herbicides such as benzsulfuron, pyrisulfuron, niazsulfuron, etc. It is also an intermediate used in medicine for sulfonamides and barbiturates.
2. Diethyl malonate can also be used for determination of ammonia and potassium in a gas chromatographic fixing solution at a maximum temperature of 40 ° C using benzene, chloroform and ethanol. Diethyl malonate is also a permitted edible spice under GB 2760-96 and is mainly used in the preparation of fruit flavors such as pear, apple, grape and cherry. .

Physicochemical Property of Diethyl malonate liquid

Colorless liquid with a sweet ether odor. It is miscible with alcohol and ether, soluble in organic solvents such as chloroform and benzene. Slightly soluble in water. The solubility in water at 20℃ is 2.08g/100ml.

Production methodprocess of Diethyl malonate liquid

Diethyl malonate liquid is obtained from the eutrope, distillation and esterification of malonic acid and ethanol in a benzene medium. It is prepared by distillation of sodium malonate and ethanol under the catalysis of sulfuric acid.

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