beta-Sitosterol Powder Raw Materials CAS 83-46-5

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Uses and synthesis of beta-Sitosterol Powder

beta-Sitosterol Powder is a class of steroid compounds that exist in nature, and although its content is small, it has a high application value. Because beta-Sitosterol CAS 83-46-5 is solid, it is also known as steroid, and it belongs to the class of macromolecular alcohols.

beta-Sitosterol Raw Materials is the main component of unsaponifiables in fats and oils. According to the different sources, sterols can be classified into three major groups, namely, animal stanols, plant stanols, and fungal stanols.

Applications / Functions of beta-Sitosterol Powder

1. beta-Sitosterol CAS 83-46-5 can lower cholesterol, relieve cough, expectorant, tumor inhibition and tissue repair. beta-Sitosterol Powder can be used as lipid-lowering drugs, used for type II hyperlipidemia, atherosclerosis and chronic bronchitis, and also used in the early stage of uterine cervical cancer and skin ulcers. beta-Sitosterol Powder can be used as a medicine raw material and health food.
2. Pharmaceutical raw materials and health food. beta-Sitosterol Raw Materials Used to supplement the diet of mice, the study found that it has a significant effect on the accumulation of body mass.
3. A kind of phytosterol, its structure is very similar to cholesterol, with estrogenic activity. beta-Sitosterol Powder
4. Inhibits proliferation (G2/M block), intranuclear replication, and polymerization of alpha-microtubule proteins and microtubules in human leukemia cells.
5. beta-Sitosterol Powder is used as a hypolipidemic agent.

Physicochemical Property of beta-Sitosterol Powder

beta-Sitosterol Raw Materials is white scale-like, needle-like crystal or crystalline powder, odorless, tasteless. mp136-140 ℃. Very soluble in chloroform and carbon disulfide, slightly soluble in ethanol or acetone, insoluble in water.

Production methodprocess of beta-Sitosterol Powder

To rice bran oil feet as raw material raw material processing to take methyl alkali soap residue at a constant temperature of 80 ℃ below the oven drying, so that the moisture content is less than 2%, to get dry soap residue, as small particles or powder. Methyl alkali soap residue [80 ℃ below] → dry soap residue extraction take dry soap residue added to the enamel reaction tank, add acetone (V soap residue: V acetone = 1: 8) stirring, jacketed distillation steam heating, reflux extraction at 50-55 ℃ 3-4h, cooled to 30 ℃ discharge at 10-15 ℃ static 12h, pressure filtration, the filtrate.

Dry soap residue [acetone] → [50-55 ° C, 3-4h] filtrate concentration, crystallization, drying the filtrate into the concentration tank, concentrated to the original volume of 1 / 5, to get the concentrate, room temperature standing crystallization 12h, filtration, to get the crude product, 60 ° C oven drying, to get the dry crude product.

Filtrate [concentration] → concentrate [crystallization] → crude products [60 ℃] → dry crude products decolorization, crystallization, drying take dry crude products plus 25-30 times 95% ethanol, add hydrochloric acid pH3-4, water bath heating, so that the crude product is dissolved, add 10-20g / L activated carbon micro-boiling for 20min, while hot, filtration, filtration, get filtrate, room temperature static crystallization of 12h, to be crystallization of the precipitation of the more complete, filtration. Collect the crystallized product, dry under vacuum at 80 ℃, get steroidal alcohol finished products. Dry crude products [decolorization] → filtrate [crystallization] → crystalline products [below 80 ℃] → beta-Sitosterol Raw Materials.

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