Chondroitin sulfate powder Raw Materials CAS 9007-28-7

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Uses and synthesis of Chondroitin sulfate powder

Chondroitin sulfate powder is white powder at room temperature, odorless and tasteless. It is highly absorbent and soluble in water to form a viscous solution. It is unstable at high temperature or acid, and is mainly deacetylated or degraded into monosaccharides or polysaccharides with small molecular weight. Chondroitin sulfate is an acidic mucopolysaccharide extracted and purified from animal cartilage. Chondroitin sulfate has different structures such as A, C, D, E, H and K. Chondroitin sulfate in nature is mostly found in the cartilage, larynx and nose bones of animals (41% in pigs), the diaphragm and trachea of cows and horses (36% to 39% in pigs). Chondroitin sulfate, as a health food or medicine, is used to prevent and treat coronary heart disease, angina pectoris, myocardial infarction, coronary atherosclerosis, myocardial ischemia and other diseases for a long time, with no obvious side effects, and can significantly reduce the morbidity and mortality of patients with coronary heart disease.

Applications/Functions of Chondroitin sulfate powder

1. Chondroitin sulfate powder is a mucopolisaccharide extracted from animal cartilage. It plays an important role in the prevention and treatment of cardiovascular diseases and joint diseases. Chondroitin sulfate powder is one of the most important biochemical products in the market.
2. Chondroitin sulfate, as a health food or medicine, is used to prevent and treat coronary heart disease, angina pectoris, myocardial infarction, coronary atherosclerosis, myocardial ischemia and other diseases for a long time, with no obvious side effects, and can significantly reduce the morbidity and mortality of patients with coronary heart disease. Long-term clinical application has found that lipids such as fat deposited on the artery and vein walls can be effectively removed or reduced, which can significantly reduce plasma cholesterol, thereby preventing the formation of atherosclerosis.
3. Chondroitin sulfate is used to treat neuralgia, neuropathic migraine, joint pain, arthritis, scapular joint pain, and pain after abdominal surgery.
4. Chondroitin sulfate powder is also used in cosmetics and as a healing agent for wounds. Chondroitin sulfate is an acid mucosaccharide, which is one of the important components of eye tissue. It can promote corneal water metabolism and improve it. It is suitable for visual fatigue and dry eye.

Physicochemical Property of Chondroitin sulfate powder

Chondroitin sulfate is a white powder at room temperature, odorless, tasteless, strong water absorption, and soluble in water to form a viscous solution. It is unstable at high temperature or acid, and is mainly deacetylated or degraded into monosaccharides or polysaccharides with small molecular weight. Insoluble in organic solvents such as ethanol, acetone and ether, its salts are more stable to heat, and are not destroyed when heated at 80℃.

Production methodprocess of Chondroitin sulfate powder

The pig's throat and nose cartilage were extracted with 2% sodium hydroxide, and the extracted liquid was hydrolyzed with crude pancreatic enzyme at 50℃ to remove impurities such as protein. Filtration, enzymatic hydrolysate to adjust pH to 6, adding ethanol to achieve 75% ethanol concentration. The precipitate obtained by centrifugation is chondroitin sulfate coarse product. Chondroitin sulfate powder was prepared by multi-step refining.

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