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Cimetidine powder Raw Materials CAS 51481-61-9
Product Overview:
Cimetidine, also known as cimetidine, tagamine, cimetidine, is an H2 receptor antagonist that can significantly inhibit the secretion of basal gastric acid during the day and night, as well as the secretion of gastric acid induced by food, histamine, pentagastrin, caffeine, and insulin. Cimetidine powder is white or white crystalline powder. Almost odorless, bitter taste. The melting point is 140-146℃. Soluble in methanol, soluble in ethanol, slightly soluble in isopropyl alcohol, slightly soluble in water, easily soluble in dilute hydrochloric acid. The saturated solution of Cimetidine is weakly alkaline.
Cimetidine powder Raw Materials CAS 51481-61-9 Attributes
MF:C10H16N6S
MW:252.34
EINECS:257-232-2
Specification:Cimetidine powder
Sample:Cimetidine powder
Brand:Cimetidine powder
Appearance: powder
Storage: Cool Dry Place
Brand: chemical Raw Materials
Shelf Life: 2 Years
Test Method: HPLC
Cimetidine powder Raw Materials CAS 51481-61-9 Details
Uses and synthesis of Cimetidine powder
Cimetidine, also known as cimetidine, tagamine, cimetidine, is an H2 receptor antagonist that can significantly inhibit the secretion of basal gastric acid during the day and night, as well as the secretion of gastric acid induced by food, histamine, pentagastrin, caffeine, and insulin. Cimetidine powder is white or white crystalline powder. Almost odorless, bitter taste. The melting point is 140-146℃. Soluble in methanol, soluble in ethanol, slightly soluble in isopropyl alcohol, slightly soluble in water, easily soluble in dilute hydrochloric acid. The saturated solution of Cimetidine is weakly alkaline.
Applications/Functions of Cimetidine powder
- Histamine H2 receptor antagonist. Cimetidine powder can inhibit the gastric acid secretion induced by histamine stimulation, the gastric acid secretion induced by food, pentaglacin, caffeine and insulin, and the basic gastric acid secretion. Cimetidine is used for gastric and duodenal ulcers, peptic esophagitis, and Chou-Aids syndrome.
- Cimetidine is used to treat peptic ulcers
Physicochemical Property of Cimetidine powder
Cimetidine White or white crystalline powder, almost odorless, bitter taste. Soluble in methanol or dilute hydrochloric acid, soluble in ethanol, slightly soluble in isopropyl alcohol, slightly soluble in water.
Production methodprocess of Cimetidine powder
The intermediate (I) and 2-aminoethylmercaptol hydrochloride react in the presence of hydrogen bromide and then neutralize with potassium carbonate to obtain the compound (II). Then it reacts with the corresponding thiourea to produce Cimetidine powder.
