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Gabapentin powder Raw Materials CAS 60142-96-3
Product Overview:
Gabapentin can be used for post-herpes infection neuralgia; For the adjuvant treatment of partial seizures in adults and children over 12 years of age with or without secondary general seizures. It can also be used for the adjuvant treatment of partial seizures in children aged 3 to 12 years. Gabapentin powder is an anti-epileptic drug first developed by the American company Warner-Lanbert and first marketed in the UK in 1993. Gabapentin is a novel antiepileptic drug, which is a derivative of gamma-aminobutyric acid (GABA). Gabapentin's pharmacological action is different from that of existing antiepileptic drugs. Recent studies have shown that Gabapentin's action is to change GABA metabolism.
Gabapentin powder Raw Materials CAS 60142-96-3 Attributes
MF:C9H17NO2
MW:171.24
EINECS:262-076-3
Specification:Gabapentin powder
Sample:Gabapentin powder
Brand:Gabapentin powder
Appearance: powder
Storage: Cool Dry Place
Brand: chemical Raw Materials
Shelf Life: 2 Years
Test Method: HPLC
Gabapentin powder Raw Materials CAS 60142-96-3 Details
Uses and synthesis of Gabapentin powder
Gabapentin can be used for post-herpes infection neuralgia; For the adjuvant treatment of partial seizures in adults and children over 12 years of age with or without secondary general seizures. It can also be used for the adjuvant treatment of partial seizures in children aged 3 to 12 years. Gabapentin powder is an anti-epileptic drug first developed by the American company Warner-Lanbert and first marketed in the UK in 1993. Gabapentin is a novel antiepileptic drug, which is a derivative of gamma-aminobutyric acid (GABA). Gabapentin's pharmacological action is different from that of existing antiepileptic drugs. Recent studies have shown that Gabapentin's action is to change GABA metabolism.
Applications/Functions of Gabapentin powder
- Gabapentin powder is a GABA analogue used for the treatment of epilepsy and neuralgia.
- Gabapentin is indicated for the additional treatment of patients with epilepsy whose localized seizures are not satisfactorily controlled or tolerated by conventional antiepileptic drugs, as well as in patients with localized seizures followed by generalized seizures. Anti-anxiety drugs.
Physicochemical Property of Gabapentin powder
From ethanol-ethyl ether crystallization, melting point 162 ~ 166℃; Melting point 165 ~ 167℃. pKal(25℃) 3.68; pKa2 10.70. Isoelectric point 7.14. The solubility exceeds 10% at pH 7.4.
Production methodprocess of Gabapentin powder
Gabapentin powder was prepared by reaction of 1, 1-cyclohexane-7, monomethyl acid (I) with ethyl chloroformate dissolved in acetone containing triethylamine and sodium azide dissolved in water. The product (II) was reflux in 20% hydrochloric acid for 3h.
