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Topiramate powder Raw Materials CAS 97240-79-4
Product Overview:
Topiramate powder, also known as Topiramate, Topeponte and Topamate, is a kind of natural monosaccharide, TWL-dextrose-sulfide. Topiramate is a white crystalline powder with bitter taste, easily soluble in alkaline solution, and the pH value of saturated solution is 6.3. Along with feaminate, lamotrigine and aminohexenoic acid, Topiramate powder can be used to control different types of epilepsy, showing good efficacy and drug activity
Topiramate powder Raw Materials CAS 97240-79-4 Attributes
MF:C12H21NO8S
MW:339.36
EINECS:619-263-3
Specification:99% min Topiramate powder
Sample:Topiramate powder
Keywords:Topiramate
Appearance:white powder
Storage: Cool Dry Place
Brand: Global ASAP Nutrition Factory
Shelf Life: 2 Years
Test Method: HPLC
Topiramate powder Raw Materials CAS 97240-79-4 Details
Anti-epileptic: For the treatment of partial-onset seizures, generalized tonic-clonic seizures, and Lennox-Gastaut syndrome in adults and children. Can be used as a single drug or in combination with other anti-epileptic drugs.
Migraine prevention: For the preventive treatment of migraine in adults
Topiramate powder's mechanism of action
Blocks voltage-dependent sodium channels: Reduces overexcitation of neurons.Enhances the activity of gamma-aminobutyric acid (GABA): GABA is an inhibitory neurotransmitter that inhibits neuronal excitability.
Antagonizes glutamate receptors (AMPA/kainate subtypes): Glutamate is an excitatory neurotransmitter and topiramate can weaken its effects.
Inhibits carbonic anhydrase: This effect may be related to its role in preventing migraines.
Target Group of Topiramate powder
Pregnant and breastfeeding women: Not allowed.
Children: Can be used to treat certain types of epilepsy, but the dose needs to be adjusted according to weight.
Elderly: The dose may need to be adjusted.
