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Trospium chloride powder Raw Materials CAS 10405-02-4
Product Overview:
Trospium chloride powder is an orally available quaternary ammonium compound with antimuscarinic properties, also known as Trospium chloride, which is chemically known as 3-2-diphenylglyoxyloxy-chloride (norscopoline-8, 1 '-pyrrolidine). RottapharmMadans is an anti-muscarine drug developed by the Italian company Rottapharmmadans, which was first marketed in Germany in 1990 and is widely used as an anti-incontinence drug in clinical practice. Trospium chloride is a quaternary ammonium compound with anticholinergic and spasmolytic properties. This product acts on the M receptor innervated by cholinergic nerve and can antagonize the effect of acetylcholine on the M receptor. The parasympathetic blocking effect of Trospium chloride powder can cause the relaxation of the smooth muscle of the bladder and increase the bladder capacity. At therapeutic doses, Trospium chloride powder had little effect on nicotinic receptors.
Trospium chloride powder Raw Materials CAS 10405-02-4 Attributes
MF:C25H30ClNO3
MW:427.96
EINECS:233-875-4
Specification:Trospium chloride powder
Sample:Trospium chloride powder
Brand:Trospium chloride powder
Appearance: powder
Storage: Cool Dry Place
Brand: chemical Raw Materials
Shelf Life: 2 Years
Test Method: HPLC
Trospium chloride powder Raw Materials CAS 10405-02-4 Details
Uses and synthesis of Trospium chloride powder
- Trospium chloride powder is an orally available quaternary ammonium compound with antimuscarinic properties, also known as Trospium chloride, which is chemically known as 3-2-diphenylglyoxyloxy-chloride (norscopoline-8, 1 '-pyrrolidine). RottapharmMadans is an anti-muscarine drug developed by the Italian company Rottapharmmadans, which was first marketed in Germany in 1990 and is widely used as an anti-incontinence drug in clinical practice. Trospium chloride is a quaternary ammonium compound with anticholinergic and spasmolytic properties.
- This product acts on the M receptor innervated by cholinergic nerve and can antagonize the effect of acetylcholine on the M receptor. The parasympathetic blocking effect of Trospium chloride powder can cause the relaxation of the smooth muscle of the bladder and increase the bladder capacity. At therapeutic doses, Trospium chloride powder had little effect on nicotinic receptors.
Applications/Functions of Trospium chloride powder
Trospium chloride powder is used to treat frequent urination, urgency, and urge incontinence caused by detrusor instability or detrusor hyperreflexes.
Physicochemical Property of Trospium chloride powder
Production methodprocess of Trospium chloride powder
Nortropinol is formed by acylation and hydrolysis from tropinol. Nortropinol reacts with 1, 4-dichlorobutane to form chlorinated (3Q-nortropinol) -8-spiro-1 '-pyrrole ammonium salt, and then reacts with diphenylglycolic acid activated amide under the catalysis of DMAP to form Trospium chloride.
