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Rifampicin powder Raw Materials CAS 13292-46-1
Product Overview:
Rifampicin powder is a broad-spectrum antibiotic drug belonging to the rifamycin family. It has a strong antibacterial effect on tuberculosis bacilli and is also effective against gram-positive or Gram-negative bacteria and viruses. Rifampicin is a red or dark red crystalline powder that is insoluble in water. Generally taken orally in capsules or tablets, Rifampicin works synergistically with other anti-TB drugs and delays the development of drug-resistant strains.
Rifampicin powder Raw Materials CAS 13292-46-1 Attributes
MF:C43H58N4O12
MW:822.94
EINECS:236-312-0
Specification:Rifampicin powder
Sample:Rifampicin powder
Brand:Rifampicin powder
Appearance: powder
Storage: Cool Dry Place
Brand: chemical Raw Materials
Shelf Life: 2 Years
Test Method: HPLC
Rifampicin powder Raw Materials CAS 13292-46-1 Details
Uses and synthesis of Rifampicin powder
Rifampicin powder is a broad-spectrum antibiotic drug belonging to the rifamycin family. It has a strong antibacterial effect on tuberculosis bacilli and is also effective against gram-positive or Gram-negative bacteria and viruses. Rifampicin is a red or dark red crystalline powder that is insoluble in water. Generally taken orally in capsules or tablets, Rifampicin works synergistically with other anti-TB drugs and delays the development of drug-resistant strains.
Applications/Functions of Rifampicin powder
- Broad-spectrum antibiotics. Rifampicin powder has antibacterial or bactericidal effect on mycobacterium tuberculosis, gram-positive bacteria and some Gram-cloudy bacteria. It is mainly used for the infection of drug-resistant tuberculosis and drug-resistant Staphylococcus aureus, and has certain curative effect on leprosy.
- Rifampicin inhibits DNA recombination and protein insertion into mature virus particles. The initiation of RNA synthesis is inhibited by binding β-subunits of RNA polymerase.
- Rifampicin is a broad spectrum antibiotic, which has strong bactericidal effect on Bacillus divergences and gram-positive and gram-negative bacteria.
Physicochemical Property of Rifampicin powder
Orange-red flake crystal or brick red crystal powder. Decomposition at 183-188℃. Soluble in chloroform and dimethyl sulfoxide, soluble in ethyl acetate, methanol and tetrahydrofuran, soluble in water (pH < 6), propanol and carbon tetrachloride.
Production methodprocess of Rifampicin powder
Rifamycin SV was oxidized to rifamycin S, then formylated with formaldehyde and tert-butylamine to form 3-formyltert-butylamine rifamycin S, then reduced with vitamin C and condensed with 1-methyl-4-aminopiperazine to prepare Rifampicin powder.
