Lenalidomide powder Raw Materials CAS 191732-72-6

MF:C13H13N3O3

MW:259.26

EINECS:691-297-1

Specification:Lenalidomide powder

Sample:Lenalidomide powder

Brand:Lenalidomide powder

Appearance: powder

Storage: Cool Dry Place

Brand: chemical Raw Materials

Shelf Life: 2 Years

Test Method: HPLC

Uses and synthesis of Lenalidomide powder

Lenalidomide powder, a ligand of the ubiquitin E3 ligase cereblon (CRBN), selectively ubiquitinates and degrades two lymphoid transcription factors IKZF1 and IKZF3 via the CRBN-CRL4 ubiquitin ligase. Lenalidomide, a derivative of Thalidomide, is also an orally active immunomodulator that acts as a molecular gel.

Applications/Functions of Lenalidomide powder

• Lenalidomide powder has multiple effects such as anti-tumor, immunomodulatory and anti-angiogenesis. It can inhibit the secretion of proinflammatory cytokines and increase the secretion of anti-inflammatory cytokines in peripheral blood mononuclear cells.
• Lenalidomide directly or indirectly induces apoptosis of tumor cells by inhibiting bone marrow stromal cell support, anti-angiogenic and anti-osteoclastic effects, and immunomodulatory activity.

Physicochemical Property of Lenalidomide powder