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Lenalidomide powder Raw Materials CAS 191732-72-6
Product Overview:
Lenalidomide powder, a ligand of the ubiquitin E3 ligase cereblon (CRBN), selectively ubiquitinates and degrades two lymphoid transcription factors IKZF1 and IKZF3 via the CRBN-CRL4 ubiquitin ligase. Lenalidomide, a derivative of Thalidomide, is also an orally active immunomodulator that acts as a molecular gel.
Lenalidomide powder Raw Materials CAS 191732-72-6 Attributes
MF:C13H13N3O3
MW:259.26
EINECS:691-297-1
Specification:Lenalidomide powder
Sample:Lenalidomide powder
Brand:Lenalidomide powder
Appearance: powder
Storage: Cool Dry Place
Brand: chemical Raw Materials
Shelf Life: 2 Years
Test Method: HPLC
Lenalidomide powder Raw Materials CAS 191732-72-6 Details
Uses and synthesis of Lenalidomide powder
Lenalidomide powder, a ligand of the ubiquitin E3 ligase cereblon (CRBN), selectively ubiquitinates and degrades two lymphoid transcription factors IKZF1 and IKZF3 via the CRBN-CRL4 ubiquitin ligase. Lenalidomide, a derivative of Thalidomide, is also an orally active immunomodulator that acts as a molecular gel.
Applications/Functions of Lenalidomide powder
- Lenalidomide powder has multiple effects such as anti-tumor, immunomodulatory and anti-angiogenesis. It can inhibit the secretion of proinflammatory cytokines and increase the secretion of anti-inflammatory cytokines in peripheral blood mononuclear cells.
- Lenalidomide directly or indirectly induces apoptosis of tumor cells by inhibiting bone marrow stromal cell support, anti-angiogenic and anti-osteoclastic effects, and immunomodulatory activity.
Physicochemical Property of Lenalidomide powder
