Ethyl cyanoformate Liquid Raw Materials CAS 623-49-4

CAS:623-49-4

MF:C4H5NO2

MW:99.09

EINECS:210-797-9

Specification:Ethyl cyanoformate Liquid

Sample:Ethyl cyanoformate Liquid

Brand:Ethyl cyanoformate Liquid

Appearance: white Liquid

Storage: Cool Dry Place

Brand: Globalchemical

Shelf Life: 2 Years

Test Method: HPLC

Uses and synthesis of Ethyl cyanoformate Liquid

Ethyl cyanoformate Liquid is a colourless transparent liquid.

Ethyl cyanoformate CAS 623-49-4 is a carboxylic acid ester derivative, which is a very important chemical intermediate, as an organic synthetic raw material, Ethyl cyanoformate Raw Materials are widely used in the fields of pharmaceuticals, pesticides, chemicals and textiles.

Applications / Functions of Ethyl cyanoformate Liquid

Ethyl cyanoformate CAS 623-49-4 is a carboxylic acid ester derivative, which is a very important chemical intermediate, as an organic synthetic raw material, Ethyl cyanoformate Raw Materials are widely used in the fields of medicine, pesticide, chemical industry and textile, etc.

Ethyl cyanoformate Liquid can be used for the production of esters, amides and heterocyclic compounds and the synthesis of pharmaceuticals, herbicides, fungicides, insecticides, and a variety of other chemicals, but also can be used as an intermediate for the synthesis of anti-infective drug cefazolin and used in the synthesis of tetrazolium acetic acid.

Physicochemical Property of Ethyl cyanoformate Liquid

Ethyl cyanoformate Raw Materials is colourless transparent liquid.

Production methodprocess of Ethyl cyanoformate Liquid

The synthesis steps of Ethyl cyanoformate Liquid are as follows:

• S1: Clean the reaction kettle, add 100KGS-1500 aromatic solvent in the reaction kettle;
• S2: Add 695KG ethyl chloroformate and 175KG hydrocyanic acid in the drop kettle;
• S3, add 30KG triethylamine catalyst and 20KG pure water to the reaction kettle, start the reaction kettle to stir and mix for 15 minutes and then stop the reaction kettle;
• S4, reduce the temperature in the reaction kettle to 2°C and then start the reaction kettle, add ethyl chloroformate and hydrocyanic acid dropwise under low-speed stirring, and control the rate of dropwise acceleration so that the dropwise addition is completed within 2 hours;
• S5, continue stirring for 30 minutes after the dropwise addition is completed to obtain a crude product of ethyl cyanocarbonate, then transfer the crude product of cyanocarbonate to a distillation tower to carry out atmospheric pressure distillation of the crude product of cyanocarbonate, remove the fraction before 90 ℃, and obtain a colourless fuming fraction at 115-116 ℃, which is a pure product of ethyl cyanocarbonate;
• S6, after the raw material is separated from ethyl cyanocarbonate by cyanidation reaction and distillation, it is then washed by sodium hydroxide in split phase to recover the catalyst.