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2-Picolinic acid powder Raw Materials CAS 98-98-6
Product Overview:
2-Picolinic acid powder is white needle crystal. Melting point 134-136 ℃, easily soluble in glacial acetic acid, almost insoluble in ether, chloroform and carbon disulfide.2-Picolinic acid CAS 98-98-6 is an important organic synthetic intermediate, used in the pharmaceutical industry for the preparation of carbocaine drugs and neurotoxicity, 2-Picolinic acid Raw Materials in the neural inhibition and local anaesthesia are widely used. 2-Picolinic acid Raw Materials are widely used in neuroleptic and local anaesthesia;
2-Picolinic acid powder Raw Materials CAS 98-98-6 Attributes
MF:C6H5NO2
MW:123.11
EINECS:202-719-7
Specification:2-Picolinic acid powder
Sample:2-Picolinic acid powder
Brand:2-Picolinic acid powder
Appearance: white powder
Storage: Cool Dry Place
Brand: Globalchemical
Shelf Life: 2 Years
Test Method: HPLC
2-Picolinic acid powder Raw Materials CAS 98-98-6 Details
Uses and synthesis of 2-Picolinic acid powder
2-Picolinic acid powder is white needle-like crystal. The melting point is 134-136℃, easily soluble in glacial acetic acid, almost insoluble in ether, chloroform and carbon disulfide.
2-Picolinic acid CAS 98-98-6 is an important organic synthetic intermediate, used in the pharmaceutical industry for the preparation of carbocaine drugs and neurotics, 2-Picolinic acid Raw Materials has a wide range of applications in neuroleptics and local anaesthesia;
Applications / Functions of 2-Picolinic acid powder
- Organic synthesis intermediates.
- 2-Methylpyridine Potassium permanganate
- Rare earth alkali metal chelates; 2-Picolinic acid powder Transition metal complexes for the preparation of picolinato ligands
Physicochemical Property of 2-Picolinic acid powder
White needle crystal. Melting point 134-136℃, easily soluble in glacial acetic acid, almost insoluble in ether, chloroform and carbon disulfide.
Production methodprocess of 2-Picolinic acid powder
- Add 50g of 2-methylpyridine to 2500ml of water, heat and stir, add 90g of potassium permanganate, about 1h and then add the second 90g of potassium permanganate.
- Add 500ml of water and continue heating for 2-2.5h until the purple colour disappears. Cool, filter out the manganese dioxide precipitate and wash with hot water. The filtrate was concentrated under reduced pressure and filtered.
- The concentrate was acidified with concentrated hydrochloric acid to the acidity of Congo red and evaporated to dryness, which was checked and refluxed with 250ml of 95% ethanol for 1h.
- Filtration, the filter cake was extracted with 95% ethanol, combined ethanol filtrate and extract, through the dry hydrogen chloride, until the crystals began to precipitate. Cooled to 10 ℃, and then pass hydrogen chloride to distillation and, filtered out 2-Picolinic acid CAS 98-98-6
