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2-iodo-1-p-tolyl-propan-1-one powder Raw Materials CAS 236117-38-7
Product Overview:
2-iodo-1-p-tolyl-propan-1-one powder, 2-iodo-1-p-tolyl-propan-1-one CAS 236117-38-7, 2-iodo-1-p-tolyl-propan-1-one Raw Materials.Pharmaceutical intermediates: used to synthesize active molecules of anti-tumor or antibacterial drugs.Functional materials: can be used as halogen modification reagents in organic synthesis
2-iodo-1-p-tolyl-propan-1-one powder Raw Materials CAS 236117-38-7 Attributes
2-iodo-1-p-tolyl-propan-1-one powder
CAS:236117-38-7
MF:C10H11IO
MW:274.1
EINECS:200-510-5
Specification:99% min 2-iodo-1-p-tolyl-propan-1-one powder
Sample:2-iodo-1-p-tolyl-propan-1-one powder
Appearance: white powder
Storage: Cool Dry Place
Brand: Ausreson
Shelf Life: 2 Years
Test Method: HPLC
2-iodo-1-p-tolyl-propan-1-one powder Raw Materials CAS 236117-38-7 Details
Uses and synthesis of 2-iodo-1-p-tolyl-propan-1-one powder
2-iodo-1-p-tolyl-propan-1-one powder, 2-iodo-1-p-tolyl-propan-1-one CAS 236117-38-7, 2-iodo-1-p-tolyl-propan-1-one Raw Materials
Applications / Functions of 2-iodo-1-p-tolyl-propan-1-one powder
2-iodo-1-p-tolyl-propan-1-one Raw Materials are used as organic and pharmaceutical intermediates.
1. Chemical synthesis applications
Pharmaceutical intermediates: commonly used in the synthesis of anti-tumor, antibacterial and other drug active molecules as key structural modification reagents.
Functional material preparation: used as a halogen functionalization reagent in organic optoelectronic materials or polymer modification.
2. Reaction characteristics
Active site: The α-iodine ketone structure makes it easy to participate in coupling, substitution and other reactions, and is suitable for the construction of complex organic skeletons.
3. Other potential applications
Research applications: may be used as a probe or marker in metal organic chemistry research
Could you provide the detailed synthesis steps for this compound?
Starting material:
Using 4-methylacetophenone (p-tolyl methyl ketone) as the starting material, the iodine atom is introduced by halogenation reaction.
Key steps:
α-halogenation reaction: Under alkaline conditions (such as NaOH/EtOH), it reacts with iodine (I₂) or iodination reagents (such as NIS) to generate α-iodinated products.
Purification: Isolate the target compound by crystallization or column chromatography.
Notes:
The reaction temperature needs to be controlled (0–5℃) to avoid side reactions.
The iodination reagent may need to be in excess to ensure conversion rate
