Feed Grade Price Powder 99% DL-Methionine powder CAS 59-51-8

DL-Methionine powder CAS 59-51-8

CAS:59-51-8

MF:C5H11NO2S

MW:149.21

EINECS:200-432-1

Specification:99% min DL-Methionine powder

Sample:DL-Methionine powder

Brand:Ausreson

Appearance: white powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Uses and synthesis of DL-Methionine powder

DL-Methionine powder is white flaky crystal or crystalline powder. It has special odour. Slightly sweet taste. Melting point 281 degrees (decomposition).

PH value of 10% aqueous solution is 5.6-6.1. It has no optical rotation. DL-Methionine CAS 59-51-8 is stable to heat and air. Unstable to strong acid, may lead to demethylation.

DL-Methionine Raw Materials Soluble in water (3.3g/100ml, 25 degrees), dilute acid and dilute minus solution. Very insoluble in ethanol, almost insoluble in ether.

1. Food industry
Nutritional fortification: Used in plant foods such as oats, corn, wheat, etc., to improve the balance of amino acids and make up for the lack of natural limiting amino acids.

Food additives: used as flavorings or nutritional supplements to enhance the nutritional value of food.

2. Animal feed
Core additive: as the first or second limiting amino acid in corn-soybean meal type feed for poultry (such as chickens), pigs, dogs, cats and other animals, to enhance the utilization rate of feed protein.

Growth regulation: Promote protein synthesis in animals, participate in methylation reaction and generation of active substances (e.g. glutathione), support the development of physiological functions.

3. Pharmaceutical field
Hepatoprotective therapy: used in the auxiliary treatment of hepatitis, cirrhosis, fatty liver and toxic liver disease, improve liver function.

Amino acid preparation: as a component of compound amino acid infusion or oral preparation, supplementing essential amino acids.

4. Agricultural applications
Bio-pesticide: It can kill potato nematode (H. rostochiensis) and reduce crop pests and diseases.

5. Scientific research and biotechnology
Protein labeling: Labeling of proteins by biotin coupling technology for the study of their functions and interactions.

Drug discovery: Involved in the synthesis of antibody drug coupling (ADC) for targeted cancer therapy.

Functions of DL-Methionine powder

Suitable for the prevention and treatment of liver diseases and arsenic or benzene poisoning, DL-Methionine CAS 59-51-8 can also be used in the treatment of dysentery and chronic infectious diseases caused by protein deficiency and malnutrition.

1. DL-Methionine powder is a feed nutrient fortifier.
2. Nutritional supplements.
3. DL-Methionine Raw Materials can be used as biochemical reagents, biochemical research; used in mixed isomer labelled mammalian and insect cell culture applications.

Applications  of DL-Methionine powder

1. Feed industry
Core additives: As the first or second limiting amino acid in corn-soybean meal diets for poultry (e.g., chickens), swine, dogs, cats, etc., it significantly improves the efficiency of feed protein utilization and reduces feed consumption by about 40%.

Growth regulation: Promote protein synthesis in animals, participate in methylation reaction and the generation of active substances (such as glutathione and cysteine), and support the development of physiological functions.

2. Pharmaceutical field
Liver disease treatment: used in the auxiliary treatment of hepatitis, cirrhosis, fatty liver and toxic liver disease, improve liver function and repair liver damage.

Amino acid supplementation: as a component of compound amino acid infusion or oral preparation, to correct malnutrition caused by protein deficiency.

3. Food industry
Nutritional fortification: added to oats, corn, wheat and other plant foods to make up for the defects of natural limiting amino acids and balance nutrition.

Flavoring agent: Its derivatives (such as sea urchin flavor flavoring agent) are used for food flavor improvement.

4. Agricultural applications
Bio-pesticide: It can effectively kill potato nematode (H. rostochiensis), reduce crop pests and diseases, and ensure crop yield.

5. Scientific research and synthesis
Protein labeling and drug development: labeling proteins by biotin coupling technology or participating in the synthesis of antibody drug coupling (ADC), which can help the research of targeted cancer therapy.

Physicochemical Property of DL-Methionine powder

DL-Methionine Raw Materials White flaky crystals or crystalline powder from alcohol, slightly sweet, with special smell. No optical rotation. Soluble in water, dilute acid and dilute alkali, slightly soluble in 95% alcohol, insoluble in ether.

What is the difference between DL-methionine and L-methionine?

1. Chemical structure and sources
L-Methionine: naturally occurring L-form, an essential amino acid to be obtained through food (e.g. meat, legumes) or supplements.

DL-Methionine: Synthetic racemic mixture containing equal amounts of D-type (biologically inactive) and L-type, low synthetic cost, mainly used in animal feed.

2. Biological activity and metabolism
L-Methionine: can be directly utilized by human body, involved in protein synthesis, methyl transfer and other physiological processes.

DL-Methionine: only the L-type part is active, and the D-type needs to be converted into L-type by enzymes (e.g. D-amino acid oxidase) in the body of animals before it can be utilized.

3. Production process and application
L-Methionine: Produced by bio-fermentation or enzyme splitting, complex process, high cost, suitable for pharmaceuticals and high-end nutritional products.

DL-Methionine: produced by chemical synthesis method, simple process and high yield, mainly used in animal feed to improve protein utilization.

4. Actual effect
For animals (e.g. poultry, pigs), the bioavailability of DL-methionine is the same as that of L-methionine, as the D-type can be efficiently converted to L-type.

L-methionine is preferred for human supplementation because it does not need to be converted and is absorbed more efficiently.

Production methodprocess of DL-Methionine powder

In the presence of formic acid and copper acetate, propionaldehyde and methyl mercaptan condense to form 3-methylthiopropionaldehyde. Then mixed with sodium cyanide and ammonium bicarbonate solution.

Reacted at 90℃ to obtain methylthioethylglycolide. Without separation and purification, it can be heated to 180°C together with 28% sodium hydroxide solution and hydrolysed to produce sodium methionine. Neutralisation with hydrochloric acid gives DL-Methionine powder .