Bulk 99% L-Proline Powder CAS 147-85-3

Bulk 99% L-Proline Powder CAS 147-85-3

CAS:147-85-3

MF:C5H9NO2

MW:115.13

EINECS:205-702-2

Specification:99% min L-Proline powder

Sample:L-Proline powder Avaliable

Keywords:L-Proline

Appearance:white powder

Storage: Cool Dry Place

Brand:Global ASAP Nutrition Factory

Shelf Life: 2 Years

Test Method: HPLC

Product Name	High quality Best price food additives proline food grade 99% L-proline powder
CAS No.	29795-82-2
Appearance	White powder
MF	C5H9NO2
Purity	99% min proline powder
Keywords	L-proline,proline,L-proline powder
Storage	Keep in a cool, dry, dark location in a tightly sealed container or cylinder.
Shelf Life	24 Months
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Uses and synthesis of L-Proline powder

L-Proline powder is one of the 18 amino acids used to synthesize protein by human body. L-Proline is a non-essential amino acid. It is colorless to white crystal or crystalline powder at room temperature, slightly smelly and slightly sweet. It is highly soluble in water, difficult to dissolve in ethanol, and insoluble in ether and n-butanol. As a component of proline metabolism, L-Proline plays an important role in the body, involved in collagen synthesis, maintenance of muscle, bone and skin health, and immune regulation and other physiological functions.

Functions of L-Proline powder

1. Promote collagen synthesis and tissue repair
Core function:
L-proline is the main component of collagen (accounting for about 20% of collagen amino acids), directly participates in the formation of collagen triple helix structure, and maintains the strength and elasticity of skin, bones, cartilage, tendons and blood vessels.

Application scenarios:

Wound healing: Accelerate skin and soft tissue repair, clinically used for postoperative recovery or chronic ulcer treatment.

Joint health: As a component of articular cartilage, it may relieve osteoarthritis symptoms (often used in combination with vitamin C, because VC is a cofactor for collagen synthesis).

2. Antioxidant and cell protection
Free radical scavenging:
Proline can reduce oxidative stress by chelating metal ions (such as iron and copper) and protect cell membranes and DNA from free radical damage.

Anti-aging:
In cosmetics, it improves skin elasticity and wrinkles by promoting collagen production and reducing oxidative damage.

3. Support cardiovascular health
Arterial wall strengthening:
Collagen is an important structural protein of the vascular wall. Proline may reduce the risk of arteriosclerosis by maintaining vascular integrity.

Reduce plaque deposition:
Animal studies have shown that proline may inhibit the oxidation of low-density lipoprotein (LDL) and reduce the formation of atherosclerotic plaques.

4. Enhance immunity and anti-inflammation
Immunomodulation:
Proline metabolites (such as hydroxyproline) participate in immune cell signaling and may regulate macrophage and T cell activity.

Anti-inflammatory effect:
It reduces chronic inflammatory responses by inhibiting the release of proinflammatory factors (such as TNF-α, IL-6).

5. Brain function and neuroprotection
Neurotransmitter synthesis:
As a glutamate precursor, it indirectly affects the production of gamma-aminobutyric acid (GABA) and regulates neural excitability.

Anti-neurodegenerative lesions:
Experimental studies have found that proline may reduce the aggregation of beta-amyloid protein (associated with Alzheimer's disease).

6. Exercise recovery and muscle health
Reduce muscle damage:
Proline supplementation may reduce muscle breakdown after intense exercise and accelerate repair (better when used in combination with glycine and arginine).

Energy metabolism: Under stress, proline can be converted into glucose to provide energy for muscles.

7. Plant and microbial stress resistance (indirect application)
Osmoregulation: Plants accumulate proline under drought and salinity stress to protect cells from dehydration. This mechanism is used in the development of genetically modified crops.

Industrial fermentation: Microorganisms use proline as an osmotic protectant to improve fermentation efficiency (such as probiotic production).

8. Applications in beauty and skin care products
Moisturizing and anti-wrinkle: As a natural moisturizing factor (NMF) component, it enhances the skin's ability to lock in moisture; stimulates collagen production and reduces wrinkles.

Barrier repair: Used in sensitive skin repair products to strengthen the structure of the stratum corneum (such as compounding with ceramide).

9. Other potential effects
Liver protection: Animal experiments show that proline may reduce liver damage caused by alcohol or toxins.

Intestinal health: As an energy source for intestinal mucosal cells, it may improve intestinal barrier function

Application of L-Proline powder

1. ‌Medical field‌
‌Drug synthesis‌: As an intermediate of antihypertensive drugs captopril and enalapril, it is used to treat hypertension and congestive heart failure.

‌Nutritional supplement‌: Used for compound amino acid infusion, treatment of malnutrition, protein deficiency, postoperative protein supplementation, etc.

‌Immunomodulation‌: It has the function of enhancing immunity and can be used for the development of related drugs.

2. ‌Food industry‌
‌Nutritional supplements‌: As a food additive, it is used in dairy products, meat products, baked goods, beverages, etc. to enhance nutritional value and flavor.

‌Flavoring agent‌: It is heated with sugar to generate special flavor substances and is used as a spice.

3. ‌Scientific research field‌
‌Biochemical research‌: Used to study protein folding, amino acid metabolism and cell growth regulation.

‌Fluorescent labeling‌: FITC-labeled L-proline is used for cell uptake research, fluorescence imaging and nutrient absorption evaluation.

4. ‌Industrial Application‌
‌Organic Synthesis‌: As a catalyst, it participates in asymmetric aldol cyclization and Michael addition reactions.

‌Collagen Precursor‌: It is a precursor of hydroxyproline and is used in the synthesis of collagen.

5. ‌Agriculture and Daily Chemicals‌
‌Agricultural Application‌: As a plant growth regulator, it promotes the healthy growth of crops.

‌Daily Chemicals‌: Used in skin care products and cosmetics to exert its antioxidant and moisturizing functions.

Production methodprocess of L-Proline powder

L-Proline powder can be synthesized by cyclization, hydroreduction and hydrolysis of pyrrolidone