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Manufacturers telmisartan raw Powder
Product Overview:
Telsalmitan ARB heart failure has angiotensin II receptor blockers, drug classification; main treatment indications include hypertension, antihypertensive drugs, and cardiovascular disease-related diseases. In addition, it can also treat heart failure: one of the treatment indications. Diabetes: often used in combination with hypertension. Kidney disease: protect kidney function. Myocardial infarction: prevent cardiovascular events. Stroke: prevent cardiovascular events. Sustained release: drug dosage form. Tablets: common dosage form. Original drug: refers to drugs produced by the original manufacturer. Generic drugs refer to drugs that imitate original drugs. Can be used in a variety of industries
Manufacturers telmisartan raw Powder Attributes
CAS:144701-48-4
MF:C33H30N4O2
MW:514.62
EINECS:620-494-7
Specification: 99% min telmisartan powder
Sample:telmisartan powder
Packaging:1kg/bag, 25kg/drum
Brand:Global ASAP Nutrition Factory
Appearance:white powder
Shelf Life: 2 Years
Test Method: HPLC
Manufacturers telmisartan raw Powder Details
Description of telmisartan powder.
China Suppliers Global ASAP Nutrition Factory Supply Telmisartan is used alone or in combination with other medications to treat high blood pressure.
Manufacturers high purity Telmisartan is also used to decrease the chance of heart attack, stroke, or death in people 55 years of age or older who are at high risk for cardiovascular disease.
Application Areas of telmisartan powder.
Telmisartan is an orally effective, specific angiotensin II receptor (AT1 type) antagonist. This product can selectively bind to AT1 receptors, and has a long-lasting effect, which can increase the level of angiotensin II.
Ancel (mainly used to lower blood pressure, and can also be used for patients (age 55 years and above) who are at high risk of serious cardiovascular events and cannot receive angiotensin converting enzyme) inhibitors to reduce the risk of myocardial infarction, stroke or death caused by cardiovascular disease.
Telmisartan can reduce aldosterone levels, but does not inhibit human plasma renin activity or block ion channels, and does not inhibit angiotensin converting enzyme (ACE, kininase II). Therefore, the use of telmisartan will not enhance bradykinin-mediated adverse reactions.
Function of telmisartan.
Telmisartan tablets, also known as Anerqiang and Micardo, have the function of protecting important organs such as the heart, brain, and kidneys. They can lower the systolic and diastolic blood pressure of hypertensive patients without affecting the heart rate. They are often used to treat primary hypertension in adults. They can also reduce the risk of myocardial infarction, stroke, cardiovascular disease, and coronary artery disease in patients aged 55 and above.
Product Method of telmisartan.
2-n-propyl-4-methylbenzimidazole-6-carboxylic acid and N-methyl-o-phenylenediamine react in paraformaldehyde at 150°C to form 2-n-propyl-4-methyl-6-(1-methylbenzimidazole-2-yl)benzimidazole. Then, it is alkylated with tert-butyl 2-(4-bromomethylphenyl)benzoate in dimethyl sulfoxide in the presence of potassium tert-butoxide. The obtained product is hydrolyzed in dimethylformamide under the action of trifluoroacetic acid to obtain telmisartan.
