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Cetilistat powder Usage and Synthesis.
The biggest advantage of Xinlisi is that it does not act on the nervous system, does not affect the activity of other enzymes in the gastrointestinal tract, is not absorbed and does not enter the blood, does not suppress appetite, and does not require dietary restrictions. Oily stools can appear 24 hours after taking the drug (a large number of oil droplets floating on the water surface), which means that undigested fat is eliminated. Xinlisisi has a similar mechanism of action to Roche's Xenical (Orlistat), but compared with the latter, it has much fewer adverse reactions such as fecal incontinence and gastrointestinal flatulence. It is safer than Xenical and has better tolerance.
Uses of Cetilistat powder.
1. A new type of weight loss drug; this product is used to treat obesity and type II, and has a similar mechanism of action to orlistat (Roche's orlistat, Xenical), which is an artificial pancreatic lipase inhibitor.
2. Neolistat is a new lipase inhibitor Neolistat (ATL-962) is used to reduce weight in obese patients.
Pharmacological Action of Cetilistat.
Xinlisistat is a long-acting and potent specific gastrointestinal lipase inhibitor. It exerts its therapeutic effect by forming a covalent bond with the active serine site of gastric lipase and pancreatic lipase in the stomach and small intestine to inactivate the enzyme. The inactivated enzyme cannot hydrolyze the fat in the food, mainly triglycerides, into absorbable free fatty acids and monoacylglycerols. Undigested triglycerides cannot be absorbed by the body, thereby reducing calorie intake and controlling weight.
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