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Product details
Esomeprazole magnesium powder, also known as levo-omeprazole, Esotaprazole, chemical name (S)-(-) -5-methoxy-2 -{[(4-methoxy-3, 5-dimethyl-2-pyridyl) methyl] sulfonyl} -1h-benzimidazole magnesium salt, It is a magnesium salt preparation of (S)-(-)- type single enantiomer of omeprazole, which was developed by AstraZeneca of Sweden and listed in China in 2004; Esomeprazole magnesium is a new type of proton pump inhibitor, which can inhibit H+/K+ -ATPase activity, and is mainly used in the treatment of gastric ulcer, duodenal ulcer and reflux esophagitis and other digestive system diseases caused by excessive gastric acid secretion.
Applications/Functions of Esomeprazole magnesium powder
Physicochemical Property of Esomeprazole magnesium powder
Production methodprocess of Esomeprazole magnesium powder
First, the preparation of esomeprazole, by sulfhydryl substituted benzimidazole and methoxypyridine condensation to produce omeprazole, esomeprazole under selective oxidation or chiral resolution. The second step is the formation of Esomeprazole magnesium powder with inorganic magnesium salts in an organic solvent or water.
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