Fluconazole powder Raw Materials CAS 86386-73-4

MF:C13H12F2N6O

MW:306.27

EINECS:627-806-0

Specification:Fluconazole powder

Sample:Fluconazole powder

Brand:Fluconazole powder

Appearance: powder

Storage: Cool Dry Place

Brand: chemical Raw Materials

Shelf Life: 2 Years

Test Method: HPLC

Uses and synthesis of Fluconazole powder

Fluconazole powder is a broad spectrum antifungal drug used for the treatment of fungal infections, which has therapeutic effects on both human and animal fungal infections. Fluconazole white to yellowish white crystalline powder, slightly odorous and bitter. Easily soluble in glacial acetic acid, methanol or ethanol, insoluble in water, and barely soluble in ether, Fluconazole powder is a new triazole antifungal infection drug, which was first developed by Pfizer in the United States and is a systemic antifungal product with broad spectrum antifungal action. Fluconazole is highly selective for its inhibition of fungal cytochrome P-450-dependent enzymes, and is also a potent and specific inhibitor of fungal alcohol synthesis.

Applications/Functions of Fluconazole powder

Fluconazole powder is mainly used for vaginal candidiasis, thrush, atrophic oral candidiasis, fungal meningitis, pulmonary fungal infection, abdominal infection, urinary tract infection and skin fungal infection.

Physicochemical Property of Fluconazole powder

Fluconazole is white or white-like crystal or crystalline powder. Odorless or slightly peculiar odor, bitter taste. Fluconazole powder is easily soluble in methanol, soluble in ethanol, slightly soluble in dichloromethane, water or acetic acid, and insoluble in ether.

Production methodprocess of Fluconazole powder

Fluconazole powder can be obtained by reaction of 2, 4-difluorobenzoate methyl ester with 1-chloromethyl-1, 2, 4-triazole with Grignard reagent and hydrolysis.